Evidence map›Paper›PMID 41051267›Full record

Observational studyBalkan medical journal2026

Depressive Symptoms and Risk of Hearing Loss Among Adults Aged 55 Years and Older: A Population-Based Study.

Erjie Xie, Yuedi Tang

Abstract readObservational Study
In one paragraph

Observational study in Balkan medical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Erjie XieDepartment of Otolaryngology-Head and Neck Surgery, West China Hospital, Sichuan University, Sichuan, China.ORCID 0009-0007-4721-9789
Yuedi TangDepartment of Otolaryngology-Head and Neck Surgery, West China Hospital, Sichuan University, Sichuan, China.ORCID 0000-0002-7193-5095

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Depression and hearing loss (HL) commonly occur in the aging population and may arise from shared mechanisms. Aims: To investigate the observational associations between depression and HL. Study Design: Observational study. Methods: Adults aged ≥ 55 years from three nationally representative study cohorts were included: the National Health and Nutrition Examination Survey, the Health and Retirement Study, and the English Longitudinal Study of Ageing. Multiple linear regression was applied to examine the association between depressive severity and audiometric thresholds. Cox regression models were applied to evaluate the associations between depressive symptoms and HL. Results: Cross-sectional analyses revealed that depression was significantly associated with higher pure-tone average thresholds. In pooled longitudinal analyses of 6,956 participants, individuals with baseline depression exhibited a higher incidence of HL when compared to their non-depressed counterparts. Longitudinal trajectory analyses identified three significant patterns: increasing [hazard ratio (HR) 1.48, 95% confidence interval (CI) 1.09-2.21] and fluctuating (HR 1.25, 95% CI 1.12-1.39) depressive symptom trajectories as independent predictors of HL, whereas decreasing trajectories indicated no significant association. Conclusion: Depression and specific longitudinal trajectories are associated with elevated risk of HL. To further understand this association, integrated care models that synergistically address depression and HL in older adults are warranted.

Indexed as

DepressionHearing LossAgedAged, 80 and overCohort StudiesCross-Sectional StudiesFemaleHumansIncidenceLongitudinal StudiesMaleMiddle AgedNutrition SurveysProportional Hazards ModelsRisk Factors

Identifiers

PMID41051267
PMCPMC12758587

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.