Evidence map›Paper›PMID 41051172›Full record

ArticleInternational journal of cancer2026

Risk of advanced adenoma detection in colorectal cancer screening programmes according to personal characteristics and screening history.

Mercedes Vanaclocha-Espí, Paula Romeo-Cervera, Susana Castan-Cameo, Elena Pérez-Sanz, Josefa Ibañez, Cristóbal Llorens-Ivorra, Ruth Risueño-Albuixech, María Besó, Ana Molina-Barceló

Abstract read
In one paragraph

Article in International journal of cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mercedes Vanaclocha-EspíFoundation for the Promotion of Health and Biomedical Research-Public Health Research FISABIO-Public Health Research, Valencia, Spain.
Paula Romeo-CerveraFoundation for the Promotion of Health and Biomedical Research-Public Health Research FISABIO-Public Health Research, Valencia, Spain.
Susana Castan-CameoGeneral Directorate of Public Health, Valencia Region, Spain.
Elena Pérez-SanzGeneral Directorate of Public Health, Valencia Region, Spain.
Josefa IbañezGeneral Directorate of Public Health, Valencia Region, Spain.
Cristóbal Llorens-IvorraGeneral Directorate of Public Health, Valencia Region, Spain.
Ruth Risueño-AlbuixechGeneral Directorate of Public Health, Valencia Region, Spain.
María BesóManises Hospital, Preventive Medicine Service, Valencia, Spain.
Ana Molina-BarcelóFoundation for the Promotion of Health and Biomedical Research-Public Health Research FISABIO-Public Health Research, Valencia, Spain.

Funding

European Regional Development Fund (ERDF)Instituto de Salud Carlos III PI20/01225
6 · The paper itself

Abstract

The detection of advanced adenomas (AA) is an important benefit-relevant indicator in colorectal cancer screening programmes (CRCSP). The study hypothesis is that factors related to personal screening history and social characteristics may influence the risk of detecting AA. We performed a retrospective study of men and women aged between 50 and 69 who participated in the Valencia Region CRCSP between 2010 and 2018. Variables: sex, age, number of previous negative faecal occult blood tests (FOBT), and faecal Hb concentration in the previous FOBT (Prev-f-Hb). We analysed the risk of AA and the influence of factors related to screening history in the first screening attendance (First_A) (n = 594,242) and in the most recent screening attendance (Recent_A) (n = 388,558) for people who had participated on at least two occasions. Logistic multivariate models were used to estimate odds ratios (OR). The risk of AA in First_A was higher in men (OR = 2.59; 2.50-2.68) and in the 60-69 age group (OR = 1.62; 1.57-1.67). In Recent_A, the risk was higher in the population with a Prev-f-Hb of greater than 0 ng/mL, and this risk increased for 0.1-19.9 ng/mL, 20-39.9 ng/mL, 40-59.9 ng/mL, 60-79.9 ng/mL, and 80-99.9 ng/mL (women: OR = 1.70, OR = 3.78, OR = 7.05, OR = 9.98, OR = 14.1 and men: OR = 1.66, OR = 3.61, OR = 5.69, OR = 8.45, OR = 10.30, respectively). The risk was lower in the population with four or five previous negative FOBT (OR = 0.76, 0.68-0.85; OR = 0.53, 0.41-0.66). Demographic characteristics and screening history could be used to design risk-adapted screening strategies.

Indexed as

AdenomaColorectal NeoplasmsEarly Detection of CancerAgedFemaleHumansMaleMass ScreeningMiddle AgedOccult BloodRetrospective StudiesRisk FactorsSpainadvanced adenomascolorectal cancerearly detectionscreening

Identifiers

PMID41051172
PMCPMC12765968

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.