Evidence map›Paper›PMID 41051012›Full record

ArticleDevelopmental medicine and child neurology2026

Preverbal visual assessment for screening cerebral visual impairment: Diagnostic accuracy and clinical utility.

Karen L Harpster, Terry L Schwartz, Alaina Johnson, Reena Donofe, Li Lin, Melissa L Rice

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Article in Developmental medicine and child neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Karen L HarpsterDivision of Occupational Therapy and Physical Therapy, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.ORCID 0000-0003-1677-6367
Terry L SchwartzDivision of Pediatric Ophthalmology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Alaina JohnsonDepartment of Occupational Therapy, College of Health and Human Services, Northern Kentucky University, Highland Heights, KY, USA.ORCID 0009-0009-3721-2318
Reena DonofeDivision of Occupational Therapy and Physical Therapy, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Li LinDivision of Patient Services Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Melissa L RiceDivision of Pediatric Ophthalmology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.ORCID 0000-0002-6165-7976

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the relationship between Preverbal Visual Assessment (PreViAs) results and cerebral visual impairment (CVI) diagnosis.

methodThis single-center retrospective chart review included children who completed a CVI interdisciplinary clinic or occupational therapy vision evaluation between May 2018 and May 2023 and had a completed PreViAs. Data were extracted from the electronic medical record. Data analysis included sensitivity, specificity, area under the curve, and Fisher's exact test.

resultsOf the 205 charts screened, 98 met study criteria (81 with CVI, 17 without); ages ranged from 3 to 50 months. The mean age of children with CVI was 15.41 months (SD = 8.93) and without was 13.24 months (SD = 5.98). Among the PreViAs domains, visual processing showed the highest frequency of concern (CVI = 94%; non-CVI = 76%), while visual attention had the lowest (CVI = 72%; non-CVI = 41%). Visual processing demonstrated the highest sensitivity (93.8%), whereas visual attention showed the best balance of sensitivity (71.6%) and specificity (58.8%). Area under the curve ranged from 0.59 to 0.66. All domains demonstrated significant differences between children with and without CVI (Fisher's exact test, p < 0.05).

interpretationEffective screening tools are critical for detection of CVI. The PreViAs is a sensitive screening tool in children at high risk for CVI. Children with concerns on the PreViAs should be referred for an interdisciplinary CVI evaluation.

Indexed as

Vision DisordersVision TestsChild, PreschoolFemaleHumansInfantMaleRetrospective StudiesSensitivity and Specificity

Identifiers

PMID41051012
PMCPMC13056020

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.