Evidence map›Paper›PMID 41050875›Full record

ArticleInternational journal of cardiology. Heart & vasculature2025

Myocardial fibroblast activation imaging in prediction of cardiac functional improvement of non-ischemic heart failure.

Yao Su, Xin Liu, Ning Fu, Lina Dou, Qili Zhang, Jinxia Zhao, Qi Yang, Cunzhi Lu, Min-Fu Yang

Registry-linked trialAbstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07657650 (FAPl Imaging Assessment of Revascularization Outcome in Ischemic Heart Failure), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07657650 recruitingnot on this mapstarted 2026, after this paper: background citation

FAPl Imaging Assessment of Revascularization Outcome in Ischemic Heart Failure

TypeobservationalSponsorBeijing Chao Yang HospitalRan2026 to 2028Enrolled122ConditionsIschemic Heart FailureArmsPCI (ercutaneous coronary intervention) and CABG (coronary artery bypass grafting, commonly known as heart bypass surgery)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yao SuDepartment of Nuclear Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
Xin LiuDepartment of Radiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
Ning FuDepartment of Nuclear Medicine, Xuzhou Central Hospital, Xuzhou 221009, China.
Lina DouDepartment of Radiology, Xuzhou Central Hospital, Xuzhou 221009, China.
Qili ZhangDepartment of Cardiology, Cardiovascular Imaging Center, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
Jinxia ZhaoDepartment of Ultrasound, Xuzhou Central Hospital, Xuzhou 221009, China.
Qi YangDepartment of Radiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
Cunzhi LuDepartment of Nuclear Medicine, Xuzhou Central Hospital, Xuzhou 221009, China.
Min-Fu YangDepartment of Nuclear Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Activated myocardial fibroblasts are key contributors to cardiac fibrosis and drive progression toward heart failure (HF). This study aimed to investigate the characteristics of myocardial fibroblast activation imaging and its predictive value for improved cardiac function in non-ischemic HF. Methods: This double-center prospective study enrolled 38 patients who underwent Results: All patients exhibited intense but inhomogeneous Conclusion: Patients with non-ischemic HF showed intense but heterogeneous

Indexed as

99mTc-HFAPiCardiac functionCMRMyocardial fibroblast activationNon-ischemic heart failure

Identifiers

PMID41050875
PMCPMC12490530

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.