Evidence map›Paper›PMID 41050869›Full record

ArticleAerosol science and technology : the journal of the American Association for Aerosol Research2025

Cellular responses of lung cells cultured at an Air-liquid Interface are influenced by spatial nanoparticle deposition patterns in an

Sripriya Nannu Shankar, Amber O'Connor, Kiran Mital, Yuetong Zhang, Alex Theodore, Amin Shirkhani, Stavros Amanatidis, Gregory S Lewis, Arantzazu-Eiguren Fernandez, Trevor B Tilly and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aerosol science and technology : the journal of the American Association for Aerosol Research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sripriya Nannu ShankarDepartment of Environmental Engineering Sciences, University of Florida, Gainesville, Florida, USA.
Amber O'ConnorDepartment of Environmental & Global Health, University of Florida, Gainesville, Florida, USA.
Kiran MitalDepartment of Mechanical Engineering, University of Florida, Gainesville, Florida, USA.
Yuetong ZhangDepartment of Environmental Engineering Sciences, University of Florida, Gainesville, Florida, USA.
Alex TheodoreDepartment of Environmental Engineering Sciences, University of Florida, Gainesville, Florida, USA.
Amin ShirkhaniDepartment of Environmental Engineering Sciences, University of Florida, Gainesville, Florida, USA.
Stavros AmanatidisAerosol Dynamics Inc., Berkeley, California, USA.
Gregory S LewisAerosol Dynamics Inc., Berkeley, California, USA.
Arantzazu-Eiguren FernandezAerosol Dynamics Inc., Berkeley, California, USA.
Trevor B Tilly711 Human Performance Wing, Air Force Research Laboratory, Wright-Patterson Airforce Base, Ohio, USA.
Otmar SchmidInsitute of Lung Health and Immunity, Helmholtz Munich, Neuherberg/Munich, Germany.
Tara Sabo-AttwoodDepartment of Environmental & Global Health, University of Florida, Gainesville, Florida, USA.
Chang-Yu WuDepartment of Environmental Engineering Sciences, University of Florida, Gainesville, Florida, USA.

Funding

Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
Together: Transforming and Translating Discovery to Improve HealthTL1TR001428 · NCATS · UNIVERSITY OF FLORIDA · PI MCCORMACK, WAYNE T. · 2015 to 2023
$3.9M
Characterization of Toxicity of Airborne ENMs using Direct in Vitro ExposureR44ES030649 · NIEHS · AEROSOL DYNAMICS, INC. · PI EIGUREN FERNANDEZ, ARANTZAZU · 2020 to 2021
$985k
NCATS NIH HHS TL1 TR001428NCATS NIH HHS UL1 TR001427NIEHS NIH HHS R44 ES030649
6 · The paper itself

Abstract

The deposition of inhaled particles is typically highly localized in both the bronchial and alveolar region of the lung displaying spot-like, line-like and other deposition patterns. However, knowledge is very limited on how different deposition patterns may influence downstream cellular responses. In this study, the Dosimetric Aerosol

Indexed as

Aerosol deliveryglobal dosehot spot dosein vitro inhalation toxicologynew approach methods (NAMs)respiratory deposition

Identifiers

PMID41050869
PMCPMC12490821

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.