Evidence map›Paper›PMID 41050855›Full record

ArticlePreventive medicine reports2025

The association of Gastro-esophageal reflux disease and self-reported myocardial-infarction among World Trade Center disaster exposed persons.

Robert Brackbill, Ayda Ahmadi, Howard Alper, Jiehui Li, Shengchao Yu

Abstract read
In one paragraph

Article in Preventive medicine reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Association of COVID-19 Severity with Comorbidities: Results from the World Trade Center Health Registry.International journal of environmental research and public health · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Robert BrackbillWorld Trade Center Health Registry, Center for Population Data Health Science, New York City Department of Health and Mental Hygiene, 30-30 47th AV, Long Island City, NY 11101, United States.
Ayda AhmadiWorld Trade Center Health Registry, Center for Population Data Health Science, New York City Department of Health and Mental Hygiene, 30-30 47th AV, Long Island City, NY 11101, United States.
Howard AlperWorld Trade Center Health Registry, Center for Population Data Health Science, New York City Department of Health and Mental Hygiene, 30-30 47th AV, Long Island City, NY 11101, United States.
Jiehui LiWorld Trade Center Health Registry, Center for Population Data Health Science, New York City Department of Health and Mental Hygiene, 30-30 47th AV, Long Island City, NY 11101, United States.
Shengchao YuWorld Trade Center Health Registry, Center for Population Data Health Science, New York City Department of Health and Mental Hygiene, 30-30 47th AV, Long Island City, NY 11101, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Gastroesophageal reflux disease (GERD) is the third most prevalent condition among responders and survivors who are monitored and treated in World Trade Center Health Program. Given the evidence of a potential association between GERD and myocardial-infarction, this study used observational data from the World Trade Center Health Registry (WTCHR) located in New York City Department of Health and Mental Hygiene, to evaluate the risk of myocardial-infarction from GERD. Methods: The study used five waves of survey data from 2003 to 2020 of the WTCHR to estimate the hazard ratio for persons who reported both GERD and gastroesophageal symptoms (GERS) compared to those with no-GERD in relation to a self-reported myocardial infarction. GERD cases and no-GERD controls were matched by age and sex; pairs of cases and controls were assigned index GERD diagnosis year for start of observation. Results: With a final sample of 13,234, proportional hazard analysis yielded an unadjusted HR = 2.0 (95 % CI, 1.67, 2.49) and HR = 1.7 (95 % CI, 1.32, 2.19) after adjusting for putative confounders. Conclusions: A nearly two-fold risk of myocardial-infarction among those with 9/11 disaster related GERD is concerning given the high prevalence of GERD among persons who were exposed to the 9/11 disaster.

Indexed as

Gastroesophageal reflux diseaseSelf-reported heart attackSelf-reported myocardial infarctionSurvival analysisWTC disasterWTC longitudinal exposure cohort

Identifiers

PMID41050855
PMCPMC12491730

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.