Evidence map›Paper›PMID 41050853›Full record

ArticlePreventive medicine reports2025

A pilot study of high-intensity interval training and continuous positive airway pressure on vascular health in Thai adults with obesity, obstructive sleep apnea, and type 2 diabetes.

Kanpiraya Nithitsutthibuta, Sureeporn Uthaikhup, Nuntigar Sonsuwan, Jaruta Kunritt, Khajornsak Tragoolpua, Arisa Parameyong, Pongson Yaicharoen, Sainatee Pratanaphon

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Article in Preventive medicine reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Kanpiraya NithitsutthibutaDepartment of Physical Therapy, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Sureeporn UthaikhupDepartment of Physical Therapy, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Nuntigar SonsuwanDepartment of Otolaryngology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Jaruta KunrittDepartment of Physical Therapy, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Khajornsak TragoolpuaDepartment of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Arisa ParameyongDepartment of Physical Therapy, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Pongson YaicharoenDepartment of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Sainatee PratanaphonDepartment of Physical Therapy, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This pilot study compared the effects of high-intensity interval training (HIIT) and continuous positive airway pressure (CPAP) on vascular health in Thai adults with obesity, obstructive sleep apnea (OSA), and type 2 diabetes mellitus. Methods: Participants were recruited from a university hospital in Chiang Mai, Thailand (July 2023-April 2024). Thirty participants were age-matched and sequentially assigned to CPAP, HIIT, or usual care groups. The HIIT group completed four 4-min treadmill intervals at 85 %-95 % of maximum heart rate, three times weekly for 12 weeks. The CPAP group used CPAP ≥ four hours/night. Primary outcomes were flow-mediated dilation (FMD) and carotid intima-media thickness (CIMT). Secondary outcomes included sleep indices, blood biomarkers, and body composition. Results: Adherence was high in both HIIT (97.78 %) and CPAP (95.89 %) groups. The HIIT group showed lower CIMT than controls ( Conclusions: HIIT may benefit vascular health and OSA severity. Both HIIT and CPAP improved body mass index. Larger trials are warranted.

Indexed as

Carotid intima-media thicknessContinuous positive airway pressureFlow-mediated dilatationHigh-intensity interval trainingObstructive sleep apneaType 2 diabetes mellitus

Identifiers

PMID41050853
PMCPMC12491740

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.