Evidence map›Paper›PMID 41050828›Full record

ArticleFood chemistry. Molecular sciences2025

Integrated transcriptomic and metabolomic profiling identifies

Qingming Ren, Yingzhi Wu, Huiyu Gao, Qi Ma, Xinli Liu, Yinghui Li, Xiaoxi Zhen, Yuanhuai Han, Bin Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food chemistry. Molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qingming RenCollege of Agriculture, Shanxi Agricultural University, Taigu 030801, Shanxi, China.
Yingzhi WuCollege of Agriculture, Shanxi Agricultural University, Taigu 030801, Shanxi, China.
Huiyu GaoCollege of Agriculture, Shanxi Agricultural University, Taigu 030801, Shanxi, China.
Qi MaCollege of Agriculture, Shanxi Agricultural University, Taigu 030801, Shanxi, China.
Xinli LiuCollege of Agriculture, Shanxi Agricultural University, Taigu 030801, Shanxi, China.
Yinghui LiCollege of Agriculture, Shanxi Agricultural University, Taigu 030801, Shanxi, China.
Xiaoxi ZhenCollege of Agriculture, Shanxi Agricultural University, Taigu 030801, Shanxi, China.
Yuanhuai HanCollege of Agriculture, Shanxi Agricultural University, Taigu 030801, Shanxi, China.
Bin ZhangCollege of Agriculture, Shanxi Agricultural University, Taigu 030801, Shanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We hypothesized that key regulatory genes in the folate biosynthesis pathway could be identified through integrated multi-omics analysis and functionally validated to enhance folate accumulation in sweet potato storage roots. Folate, an essential micronutrient in plant metabolism and human diets, shows poorly characterized accumulation mechanisms in sweet potato storage roots. Comparative profiling of 26 cultivars identified low- (968-19) and high-folate (Y25) varieties. Integrated multi-omics analysis of tuber tissues across developmental stages revealed 5-methyltetrahydrofolate (5-MTHF) and 5-formyltetrahydrofolate (5-FTHF) as principal determinants of folate variation. Differential expression analysis pinpointed

Indexed as

BiofortificationMetabolomicsNutritional enhancementTranscriptomicsVitamin B9

Identifiers

PMID41050828
PMCPMC12494576

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.