ArticleCase reports in oncological medicine2025
Isolated Leptomeningeal Carcinomatosis in Urothelial Carcinoma: A Case Report of Positive CSF Cytology With Negative Imaging.
Article in Case reports in oncological medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- A Case Report of a 64-Year-Old Man With Urothelial Carcinoma With Brain and Leptomeningeal Metastases Treated With Intrathecal Methotrexate as Part of Multimodal Management.The American journal of case reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bladder cancer is one of the most common cancers worldwide; however, leptomeningeal carcinomatosis (LMC) is an uncommon and understudied complication. We report a male patient diagnosed with LMC while in apparent clinical remission of metastatic urothelial carcinoma of the bladder. He presented with headaches, vision changes, hearing impairment, and leg weakness. Imaging of the brain and spinal cord was negative; however, the cerebrospinal fluid was positive for malignant cells consistent with high-grade urothelial carcinoma, confirming the diagnosis of LMC. Conservative measures and whole-brain radiation were ineffective, and he died 2 months after his LMC diagnosis. Literature review identified 45 cases of LMC due to bladder cancer, and we summarize these data. It is unclear whether new and more effective systemic treatment approaches for urothelial carcinoma will also reduce the risk of LMC or provide better treatment for LMC, supporting a need for more study of this devastating complication.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.