Evidence map›Paper›PMID 41050384›Full record

ArticleArab journal of urology2025

Penile shear-wave elastography predicts the outcome of botulinum neurotoxin (Botox) in the management of non-responders to phosphodiesterase-5-inhibitors: A pilot study.

Mohamed Wael Ragab, Khaled Ahmed Shawky, Ahmed Zein Eldin Fathy Bendary, Abo-Almagd Mohamed Albohy

Abstract read
In one paragraph

Article in Arab journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohamed Wael RagabDepartment of Andrology, Sexology & STIs, Faculty of Medicine, Cairo University, Cairo, Egypt.ORCID https://orcid.org/0000-0001-6139-7513
Khaled Ahmed ShawkyDepartment of Diagnostic and Interventional Radiology, Faculty of Medicine, Cairo University, Cairo, Egypt.
Ahmed Zein Eldin Fathy BendaryDepartment of Diagnostic and Interventional Radiology, Faculty of Medicine, Cairo University, Cairo, Egypt.
Abo-Almagd Mohamed AlbohyDepartment of Diagnostic and Interventional Radiology, Faculty of Medicine, Cairo University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Botulinum neurotoxin (BoNT) was introduced as a minimally invasive treatment option for erectile dysfunction (ED). However, there is no proven method that predicts improvement after BoNT injection. Shear wave elastography is an emerging imaging modality that evaluates tissue stiffness. This study aims to assess the reliability of SWE in predicting BoNT response in patients with ED and phosphodiesterase 5 inhibitors (PDE-5i) non-responders. Methods: This study comprised 20 men presenting with ED and PDE-5i non-responders. Mean tissue stiffness values (TSVs) were measured by SWE, international index of erectile function (IIEF-5), erection hardness score (EHS), sexual encounter profile questions 2 and 3 (SEP-2 and SEP-3), and global assessment questionnaire (GAQ) were evaluated before and after 100 IU of BoNT injection by 6 and 12 weeks. Results: In comparison with baseline, there was a significant improvement in IIEF-5 and EHS scores after BoNT injection at 6- and 12 weeks ( Conclusion: This finding could be applied to avoid unnecessary BoNT injections in men with ED and PDE-5i non-responders.

Indexed as

botulinum neurotoxinelastographyErectile dysfunctionshear wave elastography

Identifiers

PMID41050384
PMCPMC12493597

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.