ArticleTrauma (London, England)2025
Delirium after major trauma critical care and the association with recovery at 12 months.
Article in Trauma (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Loss of C3 and CD14 reduces region-specific neuroinflammation in a murine polytrauma model.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Delirium is associated with poor outcomes in general critical care populations, but the effects on recovery in major trauma patients are less clear. This study aimed to characterise critical care trauma patients with self-reported delirium and explore the relationship with recovery at 12 months post-injury. Methods: A prospective multi-site observational study of patients admitted to four Major Trauma Centre critical care units. Follow-up questionnaires assessed quality of life and recovery using the EQ Visual Analogue Scale (EQ VAS), European Quality-of-Life Five Dimensions (EQ-5D-5L) and the 12-item World Health Organisation Disability Assessment Schedule (WHODAS) 2.0 surveys. Post-discharge support was recorded together with 'difficulties in the 30 days leading up to follow-up' (WHODAS). Results: Of the 285 severely injured adult patients who completed the follow-up questionnaires, 180 (63%) reported delirium in hospital. Traumatic brain injury was higher in the delirium group (40% vs 28%, Conclusions: Severely injured trauma critical care patients with self-reported in hospital delirium experience worse quality of life at 12 months post-injury. Psychological problems were greater after in-hospital delirium and longer-term support for these patients appears to be limited.
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