Evidence map›Paper›PMID 41050311›Full record

ArticleACS ES&T water2024

Identification of Novel Peptides Originated from Biodegradation of Microcystins Using UHPLC-HRMS/MS.

Sharmila I Thenuwara, Upasana Shrestha, Judy A Westrick, Jason F Huntley, Dragan Isailovic

Abstract read
In one paragraph

Article in ACS ES&T water, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sharmila I ThenuwaraDepartment of Chemistry and Biochemistry, University of Toledo, Toledo, Ohio 43606, United States.ORCID 0000-0002-2890-2095
Upasana ShresthaDepartment of Medical Microbiology and Immunology, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio 43614, United States.ORCID 0009-0004-2938-1270
Judy A WestrickDepartment of Chemistry, Wayne State University, Detroit, Michigan 48202, United States.ORCID 0000-0002-1712-5737
Jason F HuntleyDepartment of Medical Microbiology and Immunology, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio 43614, United States; Present Address: Department of Microbial Pathogenesis and Immunology, College of Medicine, Texas A&M University, Bryan, Texas 77807, United States.ORCID 0000-0002-0501-6103
Dragan IsailovicDepartment of Chemistry and Biochemistry, University of Toledo, Toledo, Ohio 43606, United States.ORCID 0000-0002-1094-7738

Funding

Research Experience & Training Coordination CoreP42ES030991 · NIEHS · WAYNE STATE UNIVERSITY · PI Andrea E Cassidy-Bushrow · 2022 to 2026
$13.9M
Translational Research Support CoreP30ES036084 · NIEHS · WAYNE STATE UNIVERSITY · PI Melissa A Runge-Morris · 2024 to 2026
$5.2M
The synergistic effects of climate and anthropogenic drivers on toxic cyanobacterial bloomsP01ES028939 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Gregory James Dick, David Joseph Kennedy · 2018 to 2026
$3.7M
Synthesis and quantitation of microcystins and anabaenopeptins in the Great Lakes region to establish human exposure risks via ingestion and inhalationR01ES034017 · NIEHS · WAYNE STATE UNIVERSITY · PI Andrew P Ault, Andrew Michael Fribley · 2023 to 2026
$2.3M
NIEHS NIH HHS P01 ES028939NIEHS NIH HHS P30 ES036084NIEHS NIH HHS P42 ES030991NIEHS NIH HHS R01 ES034017
6 · The paper itself

Abstract

Biodegradation of toxic cyanobacterial cyclic peptides microcystins (MCs) by heterotrophic bacteria isolated from freshwater has gained global interest as an eco-friendly approach for water treatment. This study focused on elucidating the structures of MC-LR breakdown products generated by a group of five bacteria previously isolated from Lake Erie. Three isomers of a tetrapeptide NH

Indexed as

biodegradationcyclic tripeptidehigh-resolution mass spectrometryLake Eriemicrocystinstetrapeptide isomers

Identifiers

PMID41050311
PMCPMC12490793

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.