ArticleFrontiers in neurology2025
Volume of red blood cell transfusion is a risk factor for acute ischemic stroke after non-variceal upper gastrointestinal bleeding.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To determine if the volume of red blood cell (RBC) transfusion is a risk factor for acute ischemic stroke (AIS) in patients with non-variceal upper gastrointestinal bleeding (NVUGIB). Methods: NVUGIB patients who received RBC transfusion between January 2019 and December 2021 were included. Patients were divided into two groups, AIS group and non-AIS group. Propensity score matching was used to match the confounding factors between the two groups. Multivariate logistic regression was used to analyze independent risk factor for AIS in NVUGIB patients. The ROC curve was used to assess the sensitivity and specificity of the factors. Results: The study included 272 NVUGIB patients who received RBC transfusions, with 44 patients in the AIS group and 228 patients in the non-AIS group. After propensity score matching, 38 pairs of patients were successfully matched. Multivariate logistic regression showed that the volume of RBC transfusion was an independent risk factor for AIS in NVUGIB patients. The area under the curve for RBC transfusion volume was 0.811, the sensitivity and specificity were 0.553 and 0.921, respectively. Conclusion: The volume of RBC transfusion is a risk factor for AIS in NVUGIB patients. However, these results need to be validated by multicenter, prospective studies with larger sample sizes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.