Evidence map›Paper›PMID 41050268›Full record

ArticleInternational journal of particle therapy2025

Definitive Proton Beam Therapy for Second Primary Non-small Cell Lung Cancer After Pneumonectomy.

Masatoshi Nakamura, Kayoko Ohnishi, Toshiyuki Okumura, Den Fujioka, Keiichiro Baba, Motohiro Murakami, Masashi Mizumoto, Ikuo Sekine, Masaharu Inagaki, Yukio Sato and 1 more

Abstract read
In one paragraph

Article in International journal of particle therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Masatoshi NakamuraDepartment of Radiation Oncology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Kayoko OhnishiDepartment of Radiation Oncology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Toshiyuki OkumuraDepartment of Radiation Oncology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Den FujiokaDepartment of Radiation Oncology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Keiichiro BabaDepartment of Radiation Oncology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Motohiro MurakamiDepartment of Radiation Oncology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Masashi MizumotoDepartment of Radiation Oncology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Ikuo SekineDepartment of Medical Oncology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Masaharu InagakiDepartment of Thoracic Surgery, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Yukio SatoDepartment of Thoracic Surgery, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Hideyuki SakuraiDepartment of Radiation Oncology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the outcome of definitive proton beam therapy (PBT) for second primary non-small cell lung cancer after pneumonectomy. Patients and Methods: Between January 2006 and December 2019, 4 patients with second primary lung cancer occurring in the contralateral lung after pneumonectomy were selected from our database of patients who underwent PBT. All patients were men with a median age of 69 (range, 61-79) years at the time of PBT. The median time from pneumonectomy to PBT initiation was 104.5 (range, 92-117) months. All patients had a histology of squamous cell carcinoma and were inoperable due to poor respiratory function. Results: The median survival time was 46.6 (range, 11.7-118.4) months; 3 patients died of their primary disease and one of bacterial pneumonia. The first relapses were local recurrence inside the irradiated field ( Conclusion: Definitive PBT for new lesions in the residual lung after pneumonectomy was successful without serious adverse events, although the number of cases was small.

Indexed as

Dose-volume histogramNon–small cell lung cancerPneumonectomyProton beam therapy

Identifiers

PMID41050268
PMCPMC12493220

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.