ArticleInternational journal of particle therapy2025
Definitive Proton Beam Therapy for Second Primary Non-small Cell Lung Cancer After Pneumonectomy.
Article in International journal of particle therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: To investigate the outcome of definitive proton beam therapy (PBT) for second primary non-small cell lung cancer after pneumonectomy. Patients and Methods: Between January 2006 and December 2019, 4 patients with second primary lung cancer occurring in the contralateral lung after pneumonectomy were selected from our database of patients who underwent PBT. All patients were men with a median age of 69 (range, 61-79) years at the time of PBT. The median time from pneumonectomy to PBT initiation was 104.5 (range, 92-117) months. All patients had a histology of squamous cell carcinoma and were inoperable due to poor respiratory function. Results: The median survival time was 46.6 (range, 11.7-118.4) months; 3 patients died of their primary disease and one of bacterial pneumonia. The first relapses were local recurrence inside the irradiated field ( Conclusion: Definitive PBT for new lesions in the residual lung after pneumonectomy was successful without serious adverse events, although the number of cases was small.
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