Evidence map›Paper›PMID 41050251›Full record

ArticleActa clinica Croatica2024

SUBCLINICAL HYPOTHYROIDISM PREVALENCE AND SELENIUM LEVELS IN WOMEN OF NORTH KHORASAN, IRAN: A CROSS-SECTIONAL STUDY.

Kimiya Hadavi, Ali Esmaeili, Zeynab Moallemi, Javad Hashemi

Abstract read
In one paragraph

Article in Acta clinica Croatica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kimiya Hadavi *Student Research Committee, Faculty of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran.
Ali Esmaeili *Department of Surgery, Faculty of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran.
Zeynab MoallemiStudent Research Committee, Faculty of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran.
Javad HashemiDepartment of Pathobiology and Laboratory Sciences, Faculty of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Individuals with subclinical hypothyroidism have an increased risk of developing clinical hypothyroidism. The thyroid gland, which has the highest concentration of selenium per gram of tissue among adults, plays a crucial role in the metabolism of thyroid hormones. This study aimed to investigate the prevalence of subclinical hypothyroidism in the North Khorasan province of Iran and assess the serum selenium levels in affected individuals. We conducted a prospective study involving 550 females aged 20-55. Serum samples were collected from individuals based on the study's inclusion and exclusion criteria. We measured the serum levels of thyroid-stimulating hormone (TSH), thyroxine (T4), and triiodothyronine (T3). Subsequently, individuals with high TSH but normal T4 and T3 levels were selected for further analysis (group I). The serum levels of TSH, T4, T3 (using the ELISA method), and selenium (using the atomic absorption method) were measured and compared with those of a control group comprising healthy women matched to group I in terms of number, age, and body mass index. The overall prevalence of subclinical hypothyroidism in the study population was 6.48%. Significant differences were observed in serum TSH and selenium levels between the subclinical hypothyroidism group and the control group. Furthermore, a positive correlation between TSH and selenium levels was found exclusively within the subclinical hypothyroidism group. The occurrence of subclinical hypothyroidism was positively correlated with serum selenium levels.

Indexed as

HypothyroidismSeleniumAdultCross-Sectional StudiesFemaleHumansIranMiddle AgedPrevalenceProspective StudiesThyrotropinThyroxineTriiodothyronineYoung AdultSeleniumThyrotropinThyroxineTriiodothyronineSeleniumSubclinical hypothyroidismThyroid hormones

Identifiers

PMID41050251
PMCPMC12490480

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.