Evidence map›Paper›PMID 41050230›Full record

ArticleActa clinica Croatica2024

ACUTE GENERALIZED EXANTHEMATOUS PUSTULOSIS (AGEP) CAUSED BY ANTIBIOTIC POLYTHERAPY: A CASE REPORT.

Siniša Jolić, Zdenka Šitum Čeprnja, Toni Čeprnja, Ognjen Jolić, Mirna Šitum

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta clinica Croatica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Siniša JolićDepartment of Dermatology and Venereology, Kikinda General Hospital, Kikinda, Serbia.
Zdenka Šitum ČeprnjaDepartment of Dermatology and Venereology, Split University Hospital Center, Split, Croatia.
Toni ČeprnjaDepartment of Pathology, Split University Hospital Center, Split, Croatia.
Ognjen JolićDepartment of Chemical Engineering, Faculty of Technology, University of Novi Sad, Novi Sad, Serbia.
Mirna ŠitumDepartment of Dermatology and Venereology, Sestre milosrdnice University Hospital Center; School of Dental Medicine, University of Zagreb, Zagreb, Croatia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute generalized exanthematous pustulosis (AGEP) is a rare disease, usually associated with drug intake or infections. It is characterized by generalized acute pustules and non-follicular exanthema together with systemic symptoms. Histologically, it is characterized by a subcorneal intraepidermal spongiform pustule, papillary edema and dermal vasodilatation surrounded by a polymorphous infiltrate of neutrophils, eosinophils and mononuclear cells. The aim of this article is to present current knowledge regarding the etiology and treatment, as well as the clinical and histologic features of AGEP. We present a case of a 50-year-old male patient who was prescribed several antibiotics and developed a drug-related cutaneous adverse effect. Treatment involved rapid identification of the causative agent and its discontinuation together with supportive measures, with resolution of symptoms within two weeks. Early diagnosis and timely treatment result in a favorable outcome and prevent systemic complications.

Indexed as

Acute Generalized Exanthematous PustulosisAnti-Bacterial AgentsHumansMaleMiddle AgedAnti-Bacterial AgentsAcute generalized exanthematous pustulosisAntibioticsSevere cutaneous adverse reactions, drugs

Identifiers

PMID41050230
PMCPMC12490489

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.