Evidence map›Paper›PMID 41050209›Full record

ArticleAnimal reproduction2025

The dominant follicle: the final frontier in bovine oocyte development.

Lais Barbosa Latorraca, Antonio Galvão, Julietta Maria D'Augero, Gavin Kelsey, Noof Abdulrahman Alrabiah, Trudee Fair

Abstract read
In one paragraph

Article in Animal reproduction, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lais Barbosa LatorracaSchool of Agriculture and Food Science, University College Dublin, Dublin, Ireland.ORCID 0000-0002-0842-6319
Antonio GalvãoEpigenetics Programme, The Babraham Institute, Cambridge, United Kingdom.ORCID 0000-0002-7990-3071
Julietta Maria D'AugeroSchool of Agriculture and Food Science, University College Dublin, Dublin, Ireland.ORCID 0009-0005-7954-1540
Gavin KelseyEpigenetics Programme, The Babraham Institute, Cambridge, United Kingdom.ORCID 0000-0002-9762-5634
Noof Abdulrahman AlrabiahSchool of Agriculture and Food Science, University College Dublin, Dublin, Ireland.ORCID 0000-0002-7734-8545
Trudee FairSchool of Agriculture and Food Science, University College Dublin, Dublin, Ireland.ORCID 0000-0002-5079-8589

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The acquisition of oocyte competence in cattle, encompassing both cytoplasmic and nuclear maturation, is essential for successful fertilization and embryonic development. This competence is progressively achieved during the latter stages of the oocyte growth phase and completed within the dominant follicle (DF). The unique hormonal and immunological environment of the DF during oestrous supports oocyte "capacitation," a process involving organelle reorganization, mRNA storage and meiosis resumption, which fully prepares the oocyte for fertilization. These changes differentiate oocytes from the DF from those of subordinate follicles, explaining why only oocytes from the DF mature and ovulate successfully. Despite advances in assisted reproductive technologies like in vitro maturation (IVM) and in vitro fertilization (IVF), developmental outcomes remain inferior compared to in vivo matured oocytes, largely due to incomplete or altered oocyte maturation

Indexed as

DNA methylationdominant follicleoocyte competenceRNA sequencing

Identifiers

PMID41050209
PMCPMC12490830

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.