Evidence map›Paper›PMID 41050195›Full record

ArticleSynthetic and systems biotechnology2026

Engineering riboflavin-overproducing

Sijia Wang, Qiyao Zhu, Chuan Liu, Huina Dong, Miaomiao Xia, Zhaoxia Jin, Dawei Zhang

Abstract read
In one paragraph

Article in Synthetic and systems biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Synthetic and systems biotechnology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sijia WangSchool of Biological Engineering, Dalian Polytechnic University, Dalian, 116034, China.
Qiyao ZhuSchool of Biological Engineering, Dalian Polytechnic University, Dalian, 116034, China.
Chuan LiuTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Huina DongTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Miaomiao XiaTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Zhaoxia JinSchool of Biological Engineering, Dalian Polytechnic University, Dalian, 116034, China.
Dawei ZhangTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Overexpression of genes at key metabolic nodes frequently enhances the yield of target products. However, this often leads to widespread issues with growth defect and plasmid instability. This study utilizes the riboflavin over-producer

Indexed as

Bacillus subtilisGrowth defectMetabolic nodes analysisRAMOSRiboflavinRib operon

Identifiers

PMID41050195
PMCPMC12492654

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.