Evidence map›Paper›PMID 41049987›Full record

ArticleCureus2025

Sulfasalazine-Induced Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) Syndrome in a Patient With Rheumatoid Arthritis.

Ayesha Babar, Abir Aijaz, Abdul Bhat, Amit Badshah, Zagham Hammad

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ayesha BabarAcute Medicine, Weston General Hospital, University Hospitals Bristol and Weston, Weston-super-Mare, GBR.
Abir AijazAcute and General Internal Medicine, University Hospitals Bristol and Weston, Weston-super-Mare, GBR.
Abdul BhatAcute Medicine, University Hospitals Bristol and Weston, Weston-super-Mare, GBR.
Amit BadshahAcute and General Internal Medicine, University Hospitals Bristol and Weston, Weston-super-Mare, GBR.
Zagham HammadAcute Medicine, University Hospitals Bristol and Weston, Weston-super-Mare, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Because of its non-specific presentation and slow start, drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a severe and frequently underdiagnosed hypersensitivity reaction. In this case study, we discuss a 62-year-old lady who had been using sulfasalazine treatment for rheumatoid arthritis and presented to the emergency room with an extensive erythematous rash that was particularly noticeable on her lower limbs. She was found to have eyelid puffiness, nausea, and chills as well. Based on established diagnostic criteria, imaging scans, laboratory data, and clinical indicators, DRESS syndrome was diagnosed. This case emphasizes how important it is to identify DRESS syndrome early and be more clinically vigilant by adapting a timely multidisciplinary strategy to manage it successfully and avoid major systemic consequences.

Indexed as

drug reaction with eosinophilia and systemic symptoms (dress)skin lesionssulfa drugsulfasalazinesulfasalazine-induced hypersensitivity syndrome

Identifiers

PMID41049987
PMCPMC12492724

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.