Evidence map›Paper›PMID 41049931›Full record

ArticleCureus2025

A Lifelong Battle With Crouzon Syndrome: A Detailed Case Report of Extensive Craniofacial Surgeries and Complex Psychiatric Care.

Sai Tejaswi Gillela, Palash Jaiswal, Soojae Hollowell, Mihika Nepal, Luba Leontieva

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sai Tejaswi GillelaPsychiatry, Kakatiya Medical College, Warangal, IND.
Palash JaiswalPsychiatry, Gujarat Cancer Society Medical College, Ahmedabad, IND.
Soojae HollowellPsychiatry, State University of New York Upstate Medical University, Syracuse, USA.
Mihika NepalPsychiatry, State University of New York Upstate Medical University, Syracuse, USA.
Luba LeontievaPsychiatry, State University of New York Upstate Medical University, Syracuse, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Crouzon syndrome (CS) is a rare genetic disorder characterized by the premature fusion of cranial sutures, leading to distinctive facial features and potential neurological complications. Individuals with craniofacial syndromes often face psychosocial challenges that may increase their vulnerability to mental health issues. This case report details a 55-year-old woman with CS who endured multiple complex surgeries, including brain surgery and Le Fort III advancement osteotomy, during her early years. Having experienced neglect by her biological parents and abuse within her foster care environment, these traumatic experiences likely contributed to her heightened risk for mental health issues. She was later diagnosed with post-traumatic stress disorder and borderline personality disorder and had a history of substance abuse. Despite the prevalence of such psychiatric comorbidities, the intersection between CS and mental health disorders is rarely examined in the literature. This case emphasizes the need for more research and highlights the importance of an integrated care approach to address medical and psychiatric complexities in patients with CS.

Indexed as

borderline personality disorder (bpd)craniofacial surgeriescrouzon syndromepost-traumatic stress disorder (ptsd)substance abuse

Identifiers

PMID41049931
PMCPMC12495982

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.