Evidence map›Paper›PMID 41049906›Full record

ArticleCureus2025

Intrahepatic Portosystemic Shunt Causing Hepatic Encephalopathy in a Non-cirrhotic Patient.

Hailey J Carruthers, Natalie M George, Alexander Eskandarian, Dion Harris, Arif Musa, Ali Harb

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hailey J CarruthersDepartment of Radiology, Wayne State University School of Medicine, Detroit, USA.
Natalie M GeorgeDepartment of Radiology, Michigan State University College of Osteopathic Medicine, East Lansing, USA.
Alexander EskandarianDepartment of Radiology, Wayne State University School of Medicine, Detroit, USA.
Dion HarrisDepartment of Radiology, Wayne State University School of Medicine, Detroit, USA.
Arif MusaDepartment of Radiology, Wayne State University School of Medicine, Detroit, USA.
Ali HarbDepartment of Radiology, Wayne State University School of Medicine, Detroit, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 60-year-old woman presented with persistent nausea, new-onset tremulousness, and altered mental status. Abdominal and pelvic computed tomography (CT) revealed a large intrahepatic portosystemic connection, suspicious for a portal venous malformation. She underwent two image-guided embolization procedures. The first, via a transcaval approach, reduced shunt flow and improved ammonia levels. The second, using combined transhepatic and transfemoral access, achieved complete occlusion and led to sustained clinical improvement. This case underscores the importance of considering hepatic encephalopathy in non-cirrhotic patients with altered mental status and recognizing portosystemic shunts as a potential underlying cause.

Indexed as

embolizationhepatic encephalopathyhyperammonemiaintrahepatic portosystemic shuntnon-cirrhoticvascular malformation

Identifiers

PMID41049906
PMCPMC12491620

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.