SynthesisFrontiers in oncology2025
Prevalence and prognostic value of sarcopenia in patients with bladder cancer undergoing radical cystectomy: a systematic review and meta-analysis.
Synthesis in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Robot-Assisted Radical Cystectomy: Recommendations from Latin American Experts Consensus on Surgical Strategy, Urinary Reconstruction, and Oncological and Func-tional Outcomes.International braz j urol : official journal of the Brazilian Society of UrologyArticle
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Authors and funding
5 authors.
Funding
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Abstract
Background: The relationship between sarcopenia and clinical outcomes in patients with bladder cancer (BC) has been inconsistently reported in the literature. Some studies have identified sarcopenia as a potential prognostic indicator associated with reduced survival following radical cystectomy (RC). Objectives: This study was conducted to systematically evaluate the prognostic significance of sarcopenia in patients with bladder cancer undergoing RC. Design: Systematic review and meta-analysis. Methods: We conducted a comprehensive search of multiple databases, including PubMed, EMBASE, Web of Science, Cochrane Library, CHINAHL, China National Knowledge Infrastructure (CNKI) Databases, and Wanfang Database, up to August 23, 2023, to identify both retrospective and prospective cohort studies. To assess the methodological quality of the included studies, the Newcastle-Ottawa Scale was utilized to evaluate the risk of bias. Furthermore, heterogeneity and potential publication bias were examined, and both subgroup and sensitivity analyses were performed to ensure the robustness of the findings. Results: A total of 18 studies comprising 3,110 patients were included in the quantitative synthesis. The results of meta-analysis showed that the pooled prevalence of sarcopenia was estimated to be 49% (95% CI: 41% to 57%, I Conclusion: Sarcopenia is commonly observed among patients with bladder cancer and appears to be an important prognostic indicator associated with decreased OS and CSS in those undergoing radical cystectomy. Further prospective studies are warranted to validate these findings. Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier CRD42023456724.
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