ArticleFrontiers in oncology2025
Curative response to combined targeted-immunotherapy for post-hepatectomy lymph node metastasis in sarcomatoid hepatocellular carcinoma: case report and literature review.
Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sarcomatoid hepatocellular carcinoma (SHC) is an aggressive malignancy with poor therapeutic outcomes. Current evidence supports radical surgical resection as the primary treatment modality, yet it is associated with prohibitively high postoperative recurrence rates. We report the clinical course of a 66-year-old male diagnosed with SHC. A hepatic mass (4.1 × 2.7 × 4.4 cm) was incidentally detected during routine health screening. The patient underwent laparoscopic right posterior sectionectomy, with histopathological confirmation of SHC. Superior mesenteric lymphadenopathy suspicious for metastasis developed 1 month postoperatively. Prophylactic transarterial chemoembolization was initiated, followed by 6-month tyrosine kinase inhibitor (TKI) therapy, achieving disease stabilization. However, lymph nodes progression occurred after TKI discontinuation, confirming metastatic involvement. Subsequent combined therapy (a TKI and an anti-PD-1 antibody) was administered. Notably, the patient self-discontinued treatment after two cycles, yet subsequent imaging revealed complete resolution of metastatic lymphadenopathy. No additional antitumor therapy has been administered, and the patient remains recurrence-free with 18-month overall survival confirmed by recent radiographic surveillance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.