ArticleJournal of clinical orthopaedics and trauma2025
Clinical outcomes of autogenous fibular reconstruction after en bloc resection for aggressive giant cell tumors of the distal radius: A three-year follow-up study.
Article in Journal of clinical orthopaedics and trauma, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Giant cell tumors (GCTs) are benign but locally aggressive bone tumors that predominantly affect young adults. In clinical practice, GCTs in the distal radius accounts for approximately 10 % of all cases. This makes the distal radius the third most common site after the distal femur and proximal tibia. These tumors often exhibit locally aggressive behavior and a significant recurrence rate which are common characteristics of these tumors. Several treatment strategies have been developed to manage aggressive GCTs in the distal radius. In this study, the outcomes of autogenous fibular graft reconstruction following en bloc excision of distal radius GCT were evaluated. Methods: This retrospective study included 15 patients with GCTs of the distal radius who underwent en bloc excision and subsequent reconstruction using a non-vascularized ipsilateral fibular graft. Results: The mean follow-up duration was 3.5 years. Thirteen patients were able to achieve union (86.7 %), while the remaining two cases required iliac bone grafting at 9 and 12 months. Union was subsequently achieved at 12 and 16 months, respectively. Complications included one case of infection and two cases of wrist subluxation. All patients achieved satisfactory functional outcomes, with a mean combined range of wrist motion of 103°at the last follow-up. Conclusion: Reconstruction with an autologous Aggressive GCTs of the distal radius can be reliably treated with fibular graft following en bloc resection.
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