Evidence map›Paper›PMID 41049713›Full record

ArticlePaediatrics & child health2025

Antibiotic prescribing practices for acute otitis media and community-acquired pneumonia in a pediatric emergency department.

Dara Simcha Petel, Leo Cheong, Gregory Harvey, Olivia Ostrow, Kathryn Timberlake, Michelle Science

Abstract read
In one paragraph

Article in Paediatrics & child health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dara Simcha PetelDivision of Infectious Diseases, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID https://orcid.org/0009-0002-2067-0223
Leo CheongDepartment of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.
Gregory HarveyDepartment of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.
Olivia OstrowDepartment of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.
Kathryn TimberlakeDepartment of Pharmacy, The Hospital for Sick Children, Toronto, Ontario, Canada.
Michelle ScienceDivision of Infectious Diseases, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-2855-8570

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Recent evidence-based pediatric guidelines recommend a 5-day course of amoxicillin as first-line therapy for uncomplicated acute otitis media (AOM) in children 2 years and older and community-acquired pneumonia (CAP). The objective of this study was to assess the guideline consistency of antibiotic prescriptions for AOM and CAP in a Canadian quaternary care pediatric emergency department (ED) and identify opportunities to improve antibiotic prescribing. Methods: We retrospectively reviewed antibiotic prescriptions for patients 0 to 18 years old discharged from the ED with a diagnosis of AOM or CAP from September 2022 through September 2023. Clinical information and prescription data were extracted from the electronic medical record. Analysis was completed using descriptive statistics. Results: Of 2313 retrieved records, 1143 (85%) cases of AOM and 753 (75%) cases of CAP met the inclusion criteria. Six hundred and eighty-eight (60%) AOM prescriptions and 140 (19%) CAP prescriptions were guideline-consistent. Prescriptions were not guideline-consistent largely because of antibiotic duration (62% for AOM-67% attributable to excess duration; 93% for CAP- > 99% attributable to excess duration), followed by antibiotic dosing interval (31% for AOM; 22% for CAP), antibiotic selection (17% for AOM; 6% for CAP) and antibiotic dose (8% for AOM; 2% for CAP). Of 293 patients eligible for deferred prescriptions for AOM based on age and clinical presentation, only 52% received them. Conclusions: Most guideline-discordant prescriptions for both AOM and CAP resulted from prolonged antibiotic duration. Given the frequency of these diagnoses, effective interventions to improve guideline consistency would have a significant impact at a population level.

Indexed as

Antimicrobial stewardshipbacterialInappropriate prescribingOtitis mediaPneumoniaPractice patternsQuality improvement

Identifiers

PMID41049713
PMCPMC12495507

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.