ArticleFederal practitioner : for the health care professionals of the VA, DoD, and PHS2025
Impact of Rapid Blood Culture Identification on Antibiotic De-escalation at a Veterans Affairs Medical Center.
Article in Federal practitioner : for the health care professionals of the VA, DoD, and PHS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Timely de-escalation of antibiotics improves patient outcomes and reduces costs. The BioFire FilmArray Blood Culture Identification (BCID2) panel, a rapid diagnostic technology, enables enhanced antimicrobial stewardship. This study evaluated whether BCID2 use at Veteran Health Indiana (VHI) saved time and money to prescribe optimal antibiotics from blood culture draw pre- and postimplementation. Methods: This pre-post quasi-experimental study evaluated patients with bacteremia at VHI between March 1, 2022, and October 1, 2023. Patient data were generated using electronic health records and microbiology laboratory data. A random sampling of eligible patients was included if they had a positive bacterial blood culture for which they received ≥ 1 antibiotic while hospitalized. Results: Median difference in time to organism identification was 37.8 hours in the preintervention group vs 16.9 hours in the postintervention group ( Conclusions: BCID2 use resulted in a decrease in median time to optimal antibiotics that was not statistically significant. Additional barriers to optimal antibiotic prescription should be addressed to maximize rapid blood culture identification technologies and enhance antimicrobial stewardship.
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