Evidence map›Paper›PMID 41049528›Full record

Article3 Biotech2025

Extraction and dual-phase optimization of anticancer doses of selective novel flavonoids from yangmei (

Salauddin Al Azad, Ashfaque Rahman, A K M Helal Morshed, Tahira Panah, Tamanna Naznin Shetu, Yalnaz Naseem, Sabiha Sultana, Tanzila Ismail Ema, Rukaiya Binte Yeasin, Shairin Shoheli and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in 3 Biotech, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Salauddin Al AzadKey Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122 Jiangsu People's Republic of China.ORCID 0000-0002-3035-7882
Ashfaque RahmanDepartment of Biological Data Science, New College of Interdisciplinary Arts and Sciences, Arizona State University, Tempe, AZ 85281 USA.
A K M Helal MorshedCancer Section, University Medical Center, Comilla University, Cumilla, 3506 Bangladesh.
Tahira PanahDepartment of Pathophysiology, State Key Laboratory of Esophageal Cancer Prevention and Treatment, Henan Provincial Cooperative Innovation Center For Cancer Chemoprevention, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, 450001 China.
Tamanna Naznin ShetuKey Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122 Jiangsu People's Republic of China.
Yalnaz NaseemInstitute of Drug Discovery and Development, Zhengzhou University, Zhengzhou, 450001 Henan China.
Sabiha SultanaSchool of Biological Sciences, Illinois State University, Normal, IL 61790-4120 USA.
Tanzila Ismail EmaBiomedical Sciences, College of Natural and Applied Sciences, University of Houston-Victoria, Victoria, TX 77901 USA.
Rukaiya Binte YeasinSchool of Biological Sciences, University of Adelaide, North Terrace, Adelaide, SA 5005 Australia.
Shairin ShoheliLife Sciences and Health, Universite Paris-Saclay, 15 Rue Georges Clemenceau, 91400 Orsay, France.
Salsabeel Nahar TaibVirology Lab, International Centre for Diarrheal Disease Research, Bangladesh (ICDDR,B), Dhaka, 1212 Bangladesh.
Sabbir HasanChemical and Energy Engineering, Otto Von Guericke University, 39106 Magdeburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid hormone receptor alpha (TRα) was assessed as a drug target in papillary thyroid carcinoma (PTC) using flavonoids from Supplementary Information: The online version contains supplementary material available at 10.1007/s13205-025-04543-8.

Indexed as

Anticancer activityMolecular dockingMolecular dynamics simulationPapillary thyroid carcinomaTraditional Chinese MedicineTRα knockout cell linesYangmei flavonoids

Identifiers

PMID41049528
PMCPMC12488553

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.