Evidence map›Paper›PMID 41049490›Full record

ArticleFrontiers in physiology2025

The effect of cold water intake on heart rate variability in young women: the co-activation of the sympathetic and parasympathetic branches of the autonomic nervous system.

Isidora Knežević, Borislav Tapavički, Vuk Vukosavljević, Nemanja Maletin, David Ivanov, Milica Vuletić, Dragan Burić, Otto Barak

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In one paragraph

Article in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Isidora KneževićDepartment of Physiology, Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.
Borislav TapavičkiDepartment of Physiology, Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.
Vuk VukosavljevićDepartment of Physiology, Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.
Nemanja MaletinDepartment of Physiology, Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.
David IvanovDepartment of Physiology, Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.
Milica VuletićDepartment of Physiology, Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.
Dragan BurićDepartment of Pathophysiology and Laboratory Medicine, Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.
Otto BarakDepartment of Physiology, Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Heart rate variability (HRV) reflects the autonomic nervous system's (ANS) influence on heart rate control. Daily essential activities, such as water ingestion, affect HRV. This study aims to investigate the effect of cold water intake on HRV in young, healthy females. Materials and Methods: Fourteen healthy young females participated in the study during the luteal phase of their menstrual cycle. R-R intervals were recorded using an ECG, 5 min before and 35 min after the ingestion. We used Results: Statistically significant differences were found in all HRV parameters. The Conclusion: In young healthy females, the ANS responds coordinately to cold water ingestion, activating both branches to maintain homeostasis, preventing heat loss through sympathetic activation and limiting excessive increases in blood pressure and heart rate via parasympathetic regulation.

Indexed as

autonomic nervous systemcold water intakeheart rate variabilityluteal phaseyoung females

Identifiers

PMID41049490
PMCPMC12488612

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.