Evidence map›Paper›PMID 41049458›Full record

ArticleOpen respiratory archives

[Consensus document for Severe Asthma. 2025 Update].

Francisco Javier Álvarez-Gutiérrez, Marina Blanco Aparicio, Francisco Casas Maldonado, Vicente Plaza, Gregorio Soto Campos, Francisco Javier González-Barcala, Carlos Almonacid, Ebymar Arismendi, Carlos Cabrera, Roberto Cabestre García and 18 more

Abstract readEnglish Abstract
In one paragraph

Article in Open respiratory archives. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Francisco Javier Álvarez-GutiérrezUnidad de Asma. UMQER. Hospital Universitario Virgen del Rocío, Sevilla, España.
Marina Blanco AparicioServicio de Neumología. Hospital Universitario A Coruña, A Coruña, España.
Francisco Casas MaldonadoServicio de Neumología. Hospital Universitario Clínico San Cecilio, Granada, España.
Vicente PlazaServicio de Neumología y Alergia del Hospital de la Santa Creu i Sant Pau de Barcelona, Barcelona, España.
Gregorio Soto CamposUGC de Neumología y Alergia. Hospital Universitario de Jerez, Jerez, España.
Francisco Javier González-BarcalaServicio de Neumología-Hospital Clínico Universitario de Santiago de Compostela, A Coruña, España.
Carlos AlmonacidServicio de Neumología del Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, España.
Ebymar ArismendiServei de Pneumologia, Hospital Clínic de Barcelona, Barcelona, España.
Carlos CabreraServicio de Neumología, Hospital Dr. Negrín de Gran Canaria, Las Palmas, España.
Roberto Cabestre GarcíaEnfermería de Atención Especializada en Neumología, Hospital Royo Villanova, Zaragoza, España.
José Ángel CarreteroServicio de Neumología. Hospital Royo Villanova, Zaragoza, España.
Manuel Castilla MartínezServicio de Neumología. Hospital Universitario Los Arcos del Mar Menor, Murcia, España.
José Antonio Castillo VizueteServicio de Neumología, Hospital Universitari Dexeus, Barcelona, España.
Carolina Cisneros SerranoServicio de Neumología. Hospital Universitario La Princesa. FIB La Princesa, Madrid, España.
Álvaro Gimeno Díaz de AtauriPediatría. Hospital Puerta de Hierro, Madrid, España.
David Diaz PérezServicio de a Neumología y Cirugía Torácica. Unidad de Investigación. Hospital Universitario Nuestra Señora de Candelaria, Tenerife, España.
Christian Domingo RibasServei de Pneumologia, Corporació Parc Taulí, Sabadell, España.
Juan Luis García RiveroNeumología. Hospital Universitario Marqués de Valdecilla, Santander, España.
Alejandro López NeyraNeumología Pediátrica. Hospital Ramón y Cajal, Madrid, España.
Eva Martínez MoragónServicio de Neumología, Hospital Universitario Dr Peset, Valencia, España.
Inés de Mir MessaUnitat Pneumologia, Al·lergologia Infantil i Fibrosi Quística, Hospital Universitari Vall d'Hebron, Barcelona, España.
Xavier Muñoz GallServicio Neumología Hospital Vall d'Hebron. Departamento de Biología celular, Fisiología e Inmunología Universidad Autònoma de Barcelona, Barcelona, España.
Alicia Padilla GaloUnidad de Asma, Hospital Universitario Virgen de la Victoria, Málaga, España.
Miguel Perpiñá TorderaServicio de Neumología, Hospital Universitario y Politécnico la Fe, Valencia, España.
Luis Pérez de LlanoServicio de Neumología del Hospital Universitario Lucus Augusti, Lugo, España.
Fernando Sánchez TorilServicio de Neumologia del Hospital Arnau Vilanova-Lliria de Valencia, Valencia, España.
Verónica Sanz SantiagoServicio de Pediatría, Hospital Infantil Universitario Niño Jesús, Madrid, España.
José Valverde MolinaServicio de Pediatría, Hospital Universitario Santa Lucía, Murcia, España.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe asthma is a heterogeneous syndrome with several clinical variants and often represents a complex disease requiring a specialized and multidisciplinary approach, as well as the use of multiple drugs. The prevalence of severe asthma varies from one country to another, and it is estimated that 50% of these patients present a poor control of their disease. For the best management of the patient, it is necessary to have a correct diagnosis, an adequate follow-up and undoubtedly to offer the best available treatment, including biologic treatments with monoclonal antibodies. With this objective, this consensus process was born, which began in its first version in 2018, whose goal is to offer the patient the best possible management of their disease to minimize their symptomatology. For this 2025 consensus update, a literature review was conducted by the authors, and new sections of how to treat asthma comorbidities or pediatric asthma were added, as a paragraph about monoclonal antibody switch. Subsequently, through a two-round interactive Delphi process, a broad panel of asthma experts from SEPAR and the regional pulmonology societies proposed the recommendations and conclusions contained in this document.

Indexed as

DiagnosisFollow-upMonoclonal antibodiesSevere asthmaTreatment

Identifiers

PMID41049458
PMCPMC12495165

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.