ReviewInternational journal of medical sciences2025
The Role of Calcium Signaling in Sensorineural Hearing Loss.
Review in International journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Postoperative sensorineural hearing loss associated with prolonged hypocalcemia.JCEM case reports · 2026Article
- Audiovestibular Outcomes After Parathyroidectomy in Primary Hyperparathyroidism.Laryngoscope investigative otolaryngology · 2026Article
- Transient Sensorineural Hearing Loss and Rhabdomyolysis, Associated With Chronic Kratom Use.Case reports in otolaryngology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sensorineural hearing loss (SNHL)'s incidence is on the rise, severely affecting the quality of life of patients and even causing psychological and mental damage. It also poses a heavy burden on the global healthcare system. The auditory process involves the conversion of mechanical signals generated by the vibration of the basilar membrane into electrical signals by sensory hair cells. These signals are then transmitted to the spiral ganglion neurons, which receive input from inner hair cells and relay the information to the cochlear nucleus in the brainstem, and subsequently to the auditory cortex. Calcium plays a crucial role in this process, influencing homeostasis of the cochlear environment, the mechanoelectrical transduction channels and synaptic neurotransmitter release. Due to the increasing risks associated with aging, noise exposure, ototoxic drugs, and genetic mutations, the incidence of SNHL is continuously rising. Notably, SNHL often manifests as a disruption of calcium homeostasis. Therefore, it is essential to understand the potential mechanisms of calcium signaling in SNHL, providing new insights into the pathogenesis and treatment of SNHL. This review focuses on the mechanisms of calcium signaling in SNHL, including factors affecting calcium homeostasis and potential therapeutic approaches.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.