ArticleRespirology case reports2025
The Case for Autoantibody Screening in Stone Benchtop Workers.
Article in Respirology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- The Case for Autoantibody Screening in Stone Benchtop Workers.Respirology case reports · 2025Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Occupational silica exposure is a recognised cause of respiratory diseases such as silicosis, with increasing evidence linking it to systemic autoimmune diseases. We report a case of a 40-year-old stone benchtop fabricator diagnosed with complicated silicosis through a screening program. He was initially asymptomatic apart from Raynaud's phenomenon but had an elevated antinuclear antibody (ANA) titre. Over time, he developed progressive autoimmune disease with multisystem involvement and respiratory decline. This case highlights the potential for silica exposure to trigger severe autoimmune disease and the importance of proactive autoimmune screening in high-risk occupational groups. ANA positivity in otherwise asymptomatic individuals may signal underlying or future autoimmune disease. Clinicians should maintain a high index of suspicion for autoimmune conditions in workers exposed to silica, as early detection offers the potential to mitigate long-term morbidity through earlier intervention.
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Registered trials
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