ArticleRespirology case reports2025
Treatment-Refractory Tracheobronchitis in Crohn's Disease: A Rare Pulmonary Manifestation of Inflammatory Bowel Disease.
Article in Respirology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Tracheobronchial stenosis as a rare extraintestinal manifestation of ulcerativecolitis: a case series with different therapeutic approaches.Frontiers in medicine · 2026Article
- Treatment-Refractory Tracheobronchitis in Crohn's Disease: A Rare Pulmonary Manifestation of Inflammatory Bowel Disease.Respirology case reports · 2025Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Large airway inflammation is a rare and under-recognised pulmonary manifestation of Crohn's disease. It is associated with significant morbidity and occurs independent of intestinal disease activity. Inflammation of the trachea and bronchi in inflammatory bowel diseases is typically responsive to corticosteroids or anti-tumour necrosis factor agents. In this report, we present a case of tracheobronchitis in Crohn's disease presenting with a chronic productive cough while on adalimumab. The diagnosis was made by bronchoscopy, which revealed inflammation of the trachea and main bronchi, with biopsies demonstrating squamous cell metaplasia consistent with pulmonary inflammatory bowel disease. The patient was unable to be weaned off steroids and, in the presence of an elevated fractional expired nitric oxide, dupilumab was trialled, which resulted in minimal improvement in his symptoms.
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