Evidence map›Paper›PMID 41048996›Full record

ArticleJournal of Cancer2025

CD40LG Downregulation in Lung Adenocarcinoma: A Prognostic Biomarker Linked to Immune Cell Infiltration and Survival Outcomes.

Peng Tang, Ruihao Zhang, Yuqi Zhang, Yuan Ao, Yanan Wang, Guannan Wang, Wenjun Wang, Junmei Xu, Fang Hu, Guangsheng Zhu

Abstract read
In one paragraph

Article in Journal of Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A radiotherapy-related fibrosis gene signature-based risk model for predicting prognosis and immunological features in lung adenocarcinoma.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Peng TangKey Laboratory of Digestive Cancer of Tianjin, Tianjin's Clinical Research Center for Cancer, National Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China.
Ruihao ZhangTianjin Medical University General Hospital, Tianjin 300052, People's Republic of China.
Yuqi ZhangTianjin Medical University General Hospital, Tianjin 300052, People's Republic of China.
Yuan AoTianjin Medical University General Hospital, Tianjin 300052, People's Republic of China.
Yanan WangTianjin Medical University General Hospital, Tianjin 300052, People's Republic of China.
Guannan WangTianjin Medical University General Hospital, Tianjin 300052, People's Republic of China.
Wenjun WangGomics Gene Technology Co. Ltd, Hangzhou, 310000, China.
Junmei XuGomics Gene Technology Co. Ltd, Hangzhou, 310000, China.
Fang HuTianjin Medical University General Hospital, Tianjin 300052, People's Republic of China.
Guangsheng ZhuKey Laboratory of Digestive Cancer of Tianjin, Tianjin's Clinical Research Center for Cancer, National Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BiomarkerCD40LGImmune MicroenvironmentImmunotherapy Biomarkers.LUAD

Identifiers

PMID41048996
PMCPMC12491049

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.