ArticleOncoscience2025
Lifestyle and hormonal factors affecting semen quality and sperm DNA integrity: A cross-sectional study.
Article in Oncoscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
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Authors and funding
3 authors.
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Abstract
introductionMale infertility is a growing public health concern, influenced by modifiable lifestyle factors and hormonal imbalances. However, limited data from India have evaluated their combined impact on semen quality and sperm DNA fragmentation (SDF).
methodsThis cross-sectional study included 278 men aged 21-50 years from a tertiary care centre. Semen analysis was performed according to the WHO's 6th edition guidelines. The SDF was evaluated using the Sperm Chromatin Dispersion (SCD) test. Lifestyle details, occupational exposures, and hormonal profiles (FSH, LH, testosterone, AMH, prolactin) were gathered through structured interviews and laboratory testing. Statistical analysis was conducted using SPSS, with
resultsMen aged >40 years showed a significantly elevated SDF (
conclusionsLifestyle habits and hormonal imbalances significantly affect the fertility of men. Clinical evaluation should be integrated into infertility assessments and counselling.
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