ArticleFrontiers in medicine2025
Sleep matters: the U-shaped relationship between sleep duration and overactive bladder in U.S. adults.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- U-shaped and linear associations of ketogenic diet with nocturia and overactive bladder: mediation roles of frailty and platelet-to-HDL-C ratio and the influence of physical activity.Journal of health, population, and nutrition · 2026Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: To investigate the independent and combined associations of sleep duration and sleep disorders with the risk of overactive bladder (OAB) and identify threshold effects of sleep duration on OAB. Methods: Data from the NHANES (2005-2018) were analyzed, including 27,302 adults, among whom 5,601 (20.5%) were diagnosed with OAB. Associations between sleep duration (≤ 6 h, > 6 to < 9 h, ≥ 9 h), sleep disorders, and OAB risk were assessed using multivariable logistic regression, restricted cubic splines (RCS), and smooth curve fitting, adjusting for demographic, socioeconomic, lifestyle, and health-related covariates. Results: A significant non-linear, U-shaped relationship between sleep duration and OAB risk was observed. Compared to individuals with a sleep duration of 6-9 h, those with short sleep duration (≤ 6 h) had a slightly lower risk of OAB (OR = 0.94), while those with long sleep duration (≥ 9 h) had a significantly higher risk (OR = 2.54). Self-reported sleep disorders independently elevated the risk of OAB (OR = 1.46). RCS analysis identified 6 h of sleep as a critical inflection point. Conclusion: This study reveals a U-shaped relationship between sleep duration and the risk of overactive bladder (OAB), with both short (≤ 6 h) and long (≥ 9 h) sleep durations increasing OAB risk. These findings highlight the importance of sleep management in OAB care. Behavioral interventions, including sleep hygiene education and bladder training, may help mitigate symptoms and improve patient outcomes.
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