ReviewFrontiers in medicine2025
Global trends and hotspots of inflammation in diabetic retinopathy: a literature review and bibliometric analysis.
Review in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Exercise-induced changes in systemic inflammatory biomarkers in overweight and obese populations: a bibliometric analysis and umbrella review of meta-analyses.Frontiers in immunology · 2026Pooled it
- Mapping the evolution of botanical interventions for diabetic neuropathy: a two-database bibliometric landscape from 2005 to mid-2025.Frontiers in nutrition · 2025Pooled it
- Predictive factors, timing, and management of recurrent vitreous hemorrhage after pars plana vitrectomy in advanced proliferative diabetic retinopathy.BMC ophthalmology · 2026Article
- Plasma and aqueous humor levels of Maresin-1 in patients with diabetic retinopathy.Scientific reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Diabetic retinopathy (DR) is a global public health problem, with inflammation playing a pivotal role in its progression. In this study, we aimed to assess the current research landscape of inflammation in DR and identified emerging frontiers using bibliometric analysis. Methods: Relevant publications were retrieved from the Web of Science Core Collection database, and VOSviewer and CiteSpace were used for bibliometric analysis and visualization. Results: Overall, 3,419 publications on inflammation in DR over the past 44 years were identified, exhibiting an upward trend. China had the highest number of publications, while the United States had the majority of citations. Shanghai Jiao Tong University was the most active institution, and Conclusion: We provide a systematic overview of the academic literature on inflammation in DR over the past few decades. The United States and China have been pivotal in conducting research in this field. Optical coherence tomography screening and the precise identification of inflammation in DR are likely to emerge as the next area of focus. Further understanding the roles of NLRP3 and the gut microbiota in inflammation in DR is also a potential research direction. Additionally, identifying the mechanisms of inflammation underlying DR and age-related macular degeneration is a cutting-edge and urgent research priority.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.