Evidence map›Paper›PMID 41048941›Full record

ArticleFrontiers in medicine2025

The effect of VEGF, ET-1 and TGF-β1 levels in peritoneal dialysis effluent on peritoneal solute transport function.

Xinxuan Han, Long Li, Xiangjiang Yu, Yan Jiang, Feifei Li, Shixi Luo, Xingxin Zeng, Ming Zhang

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xinxuan HanThe 945th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army, Ya'an, China.
Long LiThe 945th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army, Ya'an, China.
Xiangjiang YuThe 945th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army, Ya'an, China.
Yan JiangYa'an Traditional Chinese Medicine Hospital, Ya'an, China.
Feifei LiYucheng District People's Hospital of Ya'an, Ya'an, China.
Shixi LuoYa'an People's Hospital, Ya'an, China.
Xingxin ZengThe 945th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army, Ya'an, China.
Ming ZhangThe 945th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army, Ya'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aims to assess the impact of Vascular endothelial growth factor (VEGF), Endothelin-1 (ET-1), and Transforming growth factor-β1 (TGF-β1) levels in peritoneal dialysis effluent on peritoneal solute transport function. Methods: We included 450 patients from four hospitals, spanning from January 2016 to January 2018. Patients were categorized into low-transport (D/Pcr ≤ 0.65) and high-transport groups (D/Pcr > 0.65) based on solute transport rates. We compared the effluent levels of VEGF, ET-1, and TGF-β1 between the groups, employed Pearson's correlation for analysis, and used multivariate logistic regression to identify independent factors influencing solute transport. Results: VEGF and TGF-β1 levels were significantly higher in the high-transport group ( Conclusion: VEGF and TGF-β1 levels in peritoneal dialysis effluent are strongly correlated with solute transport function and serve as significant predictors of patient outcomes.

Indexed as

Endothelin-1peritoneal dialysis effluentperitoneal solute transport functionprognosistransforming growth factor-β1vascular endothelial growth factor

Identifiers

PMID41048941
PMCPMC12488589

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.