ArticleFrontiers in medicine2025
Dynamic CT-based body composition analysis predicts surgical risk in Crohn's disease with small bowel stenosis: a retrospective cohort study.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Reliable predictors of surgical risk in Crohn's disease (CD) with small bowel stenosis are lacking. Longitudinal CT enterography (CTE) derived body composition parameters may improve risk stratification. Aims: To evaluate whether longitudinal CTE-derived body composition changes predict surgical risk in CD patients with small bowel stenosis. Methods: This retrospective cohort study analyzed 385 CD patients between January 2018 and June 2022 with paired CTE scans. High-risk patients ( Results: There were 289 cases in the low-risk group and 96 cases in the high-risk group. Interaction terms (time and gender) were tested, males showed significant reductions in L3-L4 skeletal muscle index (SMI) ( Conclusion: Dynamic body composition parameters, particularly delta SMI and adipose tissue parameters, serve as valuable imaging biomarkers for predicting surgical necessity in CD patients with small bowel stenosis.
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