Evidence map›Paper›PMID 41048401›Full record

ArticleExploration of drug science2025

Recent exploration of γ-AApeptide based antimicrobial peptide mimics as potential therapeutics towards drug-resistant bacteria.

Jarais Fontaine, Jianfeng Cai

Abstract read
In one paragraph

Article in Exploration of drug science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jarais FontaineDepartment of Chemistry, University of South Florida, Tampa, FL 33620, USA.
Jianfeng CaiDepartment of Chemistry, University of South Florida, Tampa, FL 33620, USA.ORCID 0000-0003-3106-3306

Funding

Recognition of Abeta monomeric helixR01AG056569 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI CHUANHAI CAO, Jianfeng Cai · 2017 to 2026
$4.1M
Targeting Wnt signaling pathwayR01GM150196 · NIGMS · UNIVERSITY OF SOUTH FLORIDA · PI Jianfeng Cai · 2023 to 2026
$1.7M
NIA NIH HHS R01 AG056569NIGMS NIH HHS R01 GM150196
6 · The paper itself

Abstract

Over the last 60 years, only four new classes of antibiotics have been introduced, while the prevalence of antibiotic-resistant Gram-positive and Gram-negative bacteria has risen. This underscores the urgent need for new antibacterial therapeutics. This commentary leverages the recent exploration of γ-substituted-

Indexed as

amphipathicAntimicrobial peptidespeptidomimeticsγ-AApeptides

Identifiers

PMID41048401
PMCPMC12493093

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.