Evidence map›Paper›PMID 41048271›Full record

ArticleFrontiers in public health2025

Age and socioeconomic disparities in cervical cancer incidence and mortality: a SEER-based analysis.

Yuyi Ou, Santosh Chokkakula, Sio Mui Chong, Hao Wang, Andrew In-Cheong Si, Yong Jiang, Liying Huang, Xiaohua Xu, Chengliang Yin, Jun Lyu and 2 more

Abstract read
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In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Cervical cancer screening strategies in women 65 years and older in the human papillomavirus era: A systematic review and meta-analysis of human papillomavirus-based testing and self-sampling approaches.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yuyi Ou *Department of Gynaecology, Foshan Women and Children Hospital Affiliated to Guangdong Medical University, Foshan, China.
Santosh Chokkakula *Chungbuk National University College of Medicine and Medical Research Institute, Cheongju, Republic of Korea.
Sio Mui Chong *Department of Dermatology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
Hao WangDepartment of Gynaecology, Foshan Women and Children Hospital Affiliated to Guangdong Medical University, Foshan, China.
Andrew In-Cheong SiDepartment of Orthopedics, Clinica de Wong's, Macao, Macao SAR, China.
Yong JiangDepartment of Oncology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
Liying HuangDepartment of Clinical Research, First Affiliated Hospital of Jinan University, Guangzhou, China.
Xiaohua XuDepartment of Medicine, Shenzhen University, Shenzhen, China.
Chengliang YinFaculty of Medicine, Macao University of Science and Technology, Macao, Macao SAR, China.
Jun LyuDepartment of Clinical Research, First Affiliated Hospital of Jinan University, Guangzhou, China.
Xiaobin HuangDepartment of Gynaecology, Foshan Women and Children Hospital Affiliated to Guangdong Medical University, Foshan, China.
Hui-Ling ShangDepartment of Hospital Office, Foshan Women and Children Hospital Affiliated to Guangdong Medical University, Foshan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cervical cancer (CC) remains a significant global health challenge, with marked variations in incidence and mortality influenced by age, race, and economic status. This study examines age-related patterns in CC outcomes, focusing on racial disparities and socioeconomic factors using data from the SEER18 database. Methods: We conducted a retrospective cohort study using data from the SEER 18 registries program from 2010 to 2015. Logistic regression models were used to assess factors associated with CC presence at diagnosis. Cox proportional hazard models and competing risk models examined all-cause mortality (ACM) and cancer-specific mortality (CSM). Restricted cubic spline (RCS) analysis was employed to investigate nonlinear relationships between age and CC outcomes. Results: A total of 11,183 cases of invasive cervical cancer were identified. The study revealed significant disparities in CC outcomes based on race and socioeconomic status. Black women exhibited higher incidence and mortality rates compared to White women, with this disparity widening with age. The hazard model showed that Black race (adjusted sHR 1.199, 95% CI 1.086-1.323, Conclusion: This analysis highlights substantial racial and socioeconomic disparities in cervical cancer outcomes, exacerbated with increasing age and advanced tumor characteristics. These findings emphasize the necessity for age and population specific screening and intervention strategies to improve survival and reduce inequities among high-risk groups.

Indexed as

Health Status DisparitiesUterine Cervical NeoplasmsAdultAgedAge FactorsBlack PeopleFemaleHumansIncidenceMiddle AgedProportional Hazards ModelsRetrospective StudiesSEER ProgramSocioeconomic Disparities in HealthSocioeconomic FactorsWhite Peopleage-related patternscervical cancerincidencemortalitySEER database

Identifiers

PMID41048271
PMCPMC12491245

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.