ArticleBiology of sport2025
Are decorin gene variants associated with anterior cruciate ligament rupture susceptibility?
Article in Biology of sport, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
This study aimed to investigate whether two DCN gene single nucleotide polymorphisms (SNPs), rs13312816 (T > A) and rs516115 (A > G), are associated with the risk and severity of anterior cruciate ligament (ACL) injury. A total of 296 physically active, unrelated Caucasian males participated: 160 with noncontact ACL injuries and 136 healthy controls. Genotyping was conducted using TaqMan assays. Logistic regression and haplotype-based analyses were performed, adjusting for age and body mass. The minor A allele of rs13312816 was significantly more frequent in ACL cases than in controls (8.54% vs. 2.94%, P = 0.0047; OR = 3.08, 95% CI: 1.33-7.98). Individuals with the A/T genotype had higher odds of injury compared to T/T carriers (P
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