Evidence map›Paper›PMID 41048201›Full record

ArticleOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2025

Long-term test and retest reliability of clinical vergence testing.

Mitchell Scheiman, Aparna Raghuram, Christina Master, Matthew L Robich, Andrew Toole, Erica R Shelton, Gayathri Srinivasan, Sophia Marusic, Siva Meiyeppen, Lisa A Jordan and 2 more

Abstract readMulticenter Study
In one paragraph

Article in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

12 authors.

Mitchell ScheimanPennsylvania College of Optometry at Salus at Drexel University, Elkins Park, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-9274-5696
Aparna RaghuramBoston Children's Hospital, Boston, Massachusetts, USA.
Christina MasterChildren's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Matthew L RobichThe Ohio State University College of Optometry, Columbus, Ohio, USA.
Andrew TooleThe Ohio State University College of Optometry, Columbus, Ohio, USA.
Erica R SheltonThe Ohio State University College of Optometry, Columbus, Ohio, USA.
Gayathri SrinivasanSpencer Center for Vision Research, Byers Eye Institute at Stanford University, Stanford, California, USA.
Sophia MarusicBoston Children's Hospital, Boston, Massachusetts, USA.
Siva MeiyeppenPennsylvania College of Optometry at Salus at Drexel University, Elkins Park, Pennsylvania, USA.
Lisa A JordanThe Ohio State University College of Optometry, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0001-8389-9215
Tawna L RobertsSpencer Center for Vision Research, Byers Eye Institute at Stanford University, Stanford, California, USA.
EPICC Study Group

Funding

The OSU Center for Clinical and Translational Science: Advancing Today's Discoveries to Improve HealthUM1TR004548 · NCATS · OHIO STATE UNIVERSITY · PI CYNTHIA A GERHARDT, JULIE A. JOHNSON · 2023 to 2026
$22.0M
Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI Jeffrey L Goldberg · 2017 to 2026
$8.0M
Vision disorders in adolescents following concussionR34EY030582 · NEI · OHIO STATE UNIVERSITY · PI JORDAN, LISA A, ROBERTS, TAWNA · 2020 to 2021
$556k
NCATS NIH HHS UM1 TR004548NCATS NIH HHS UM1TR004548NEI NIH HHS P30 EY026877NEI NIH HHS P30-EY026877NEI NIH HHS R34 EY030582NEI NIH HHS R34EY030582Research to Prevent Blindness
6 · The paper itself

Abstract

purposeTo establish long-term reliability measures for vergence testing in a control population of adolescents.

methodsHealthy participants between 12 and 17.5 years with normal binocular vision were recruited from 10 clinical sites. Cover test, near point of convergence (NPC), positive and negative fusional vergences, vergence facility (12∆ base-out/3∆ base-in) and vergence jumps (using the Oculomotor Assessment Tool) were performed at the initial visit and repeated at 90 days. The mean and standard deviation were calculated for the overall group for NPC, vergence facility and vergence jumps and by prism dioptre step value for PFV and NFV (1Δ or 2Δ if below 20∆ or 5Δ above 20∆). Agreement was assessed using Bland-Altman plots and 95% limits of agreement (LOA).

resultsNinety-three participants (mean age 14.3 ± 1.7 years, 52% female) were enrolled and 91 (98%) completed the initial and 90-day outcome evaluation. The mean differences were significantly greater than zero for vergence facility (p < 0.05) and the first and second 30 s of vergence jumps (p < 0.01). The 95% LOA were narrow for NPC (±2.5) and negative fusional vergence (±5.9), suggesting good repeatability. LOA were larger for positive fusional vergence (±17.8), vergence facility (±9.8) and vergence jumps (±16.2). Analysis of the positive fusional vergence data indicates that the different step sizes (1∆ or 2∆ vs. 5∆) in the horizontal prism bar contribute to considerably larger variability in these measures.

conclusionsIn participants with normal binocular vision and no concussion history, good reliability yielded comparable results 90 days apart for all vergence measures. The results provide values that can be used to interpret the effect of intervention for vergence disorders in clinical practice and research studies. An important outcome of this study is the understanding that 5∆ steps on the typical horizontal prism bar contribute to high variability in positive fusional vergence measures when findings are ≥20∆.

Indexed as

Convergence, OcularVision, BinocularVision TestsAdolescentChildFemaleFollow-Up StudiesHealthy VolunteersHumansMaleReproducibility of ResultsTime Factorsnear point of convergencestep vergencetesting reliabilityvergencevergence amplitudesvergence facility

Identifiers

PMID41048201
PMCPMC12682085

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.