Evidence map›Paper›PMID 41048181›Full record

ArticleBJU international2025

Robot-assisted partial nephrectomy using the Hugo™ RAS System: first multicentre study and Tetrafecta achievement.

Francesco Prata, Paolo Dell'Oglio, Angelo Mottaran, Riccardo Bertolo, Stefano Tappero, Pietro Piazza, Francesca Montanaro, Alessandro Veccia, Alberto Ragusa, Alberto Caviglia and 12 more

Abstract readMulticenter Study
In one paragraph

Article in BJU international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Francesco PrataDepartment of Urology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.ORCID 0000-0003-3084-6210
Paolo Dell'OglioDepartment of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.ORCID 0000-0002-2771-2919
Angelo MottaranDivision of Urology, I.R.C.C.S. Azienda Ospedaliero-Universitaria di Bologna Policlinico Sant'Orsola, Bologna, Italy.
Riccardo BertoloUrology Unit, Department of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona, A.O.U.I, Verona, Italy.
Stefano TapperoDepartment of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.ORCID 0000-0001-9712-2685
Pietro PiazzaDivision of Urology, I.R.C.C.S. Azienda Ospedaliero-Universitaria di Bologna Policlinico Sant'Orsola, Bologna, Italy.
Francesca MontanaroUrology Unit, Department of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona, A.O.U.I, Verona, Italy.
Alessandro VecciaUrology Unit, Department of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona, A.O.U.I, Verona, Italy.
Alberto RagusaResearch Unit of Urology, Department of Medicine and Surgery, Università Campus Bio-Medico, Rome, Italy.
Alberto CavigliaDepartment of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Francesco TedescoResearch Unit of Urology, Department of Medicine and Surgery, Università Campus Bio-Medico, Rome, Italy.
Angelo CivitellaDepartment of Urology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Andrea IannuzziResearch Unit of Urology, Department of Medicine and Surgery, Università Campus Bio-Medico, Rome, Italy.
Tommaso SaccucciDepartment of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.ORCID 0009-0002-4706-4813
Giovanni MutoDepartment of Urology, GVM - Maria Pia Hospital, Turin, Italy.
Aldo Massimo BocciardiDepartment of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Eugenio BrunocillaDivision of Urology, I.R.C.C.S. Azienda Ospedaliero-Universitaria di Bologna Policlinico Sant'Orsola, Bologna, Italy.
Roberto Mario ScarpaDepartment of Urology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Alessandro AntonelliUrology Unit, Department of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona, A.O.U.I, Verona, Italy.
Riccardo SchiavinaDivision of Urology, I.R.C.C.S. Azienda Ospedaliero-Universitaria di Bologna Policlinico Sant'Orsola, Bologna, Italy.
Antonio GalfanoDepartment of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Rocco PapaliaDepartment of Urology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the perioperative outcomes and the rate of Tetrafecta achievement in robot-assisted partial nephrectomy (RAPN) cases performed using the Hugo™ robot-assisted surgery (RAS) system (Medtronic, Minneapolis, MN, USA). PATIENTS AND

methodsData from five tertiary care referral centres performing RAPN with the Hugo RAS System since October 2022 were collected. For the study purpose, a novel Tetrafecta was defined as a proxy for surgical quality. This included the coexistence of negative surgical margins, absence of intraoperative and Clavien-Dindo Grade ≥II postoperative complications, and 90-day decline in estimated glomerular filtration rate of no more than 30% from baseline.

resultsA total of 140 patients, who underwent RAPN with the Hugo RAS system, were included. The median (interquartile range [IQR]) docking, console, and total operative times were 5 (4-7) min, 79 (45.5-135) min, and 150 (96-205) min, respectively. The median (IQR) estimated blood loss was 150 (100-300) mL. No additional port placements were required, and no conversions to open surgery occurred. Overall, postoperative complications were observed in 20.7% of cases, 5% of which were classified as major (Clavien-Dindo Grade >II). Tetrafecta was achieved in 80% of cases. Multivariate logistic regression analysis showed that R.E.N.A.L. (Radius, Exophytic/Endophytic, Nearness to collecting system or sinus, Anterior/Posterior, Location) nephrometry score (odds ratio [OR] 0.69; P = 0.01) and Hugo RAS surgical experience (OR 1.03; P = 0.02) were independent predictors of Tetrafecta achievement.

conclusionsRelying on the largest multicentre series, our findings demonstrate that this novel robotic platform enables safe and effective RAPN, achieving a satisfactory Tetrafecta rate. These results would support the adoption of the Hugo RAS system to perform RAPN.

Indexed as

Kidney NeoplasmsNephrectomyRobotic Surgical ProceduresAgedFemaleHumansMaleMargins of ExcisionMiddle AgedOperative TimePostoperative ComplicationsRetrospective StudiesTreatment OutcomedockingHugo RAS systemnephron‐sparing surgerypartial nephrectomyrenal neoplasmroboticTetrafecta

Identifiers

PMID41048181
PMCPMC12606541

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.