Evidence map›Paper›PMID 41048067›Full record

ArticlePlant, cell & environment2026

Seed-Borne Spirosoma pollinicola in Commercial Hazelnuts: A Global Survey of Microbial Presence and Allergen Diversity.

Barbara Karpinska, Alessandro Fiocchi, Marta Biolatti, Ileana Manera, Christine Helen Foyer

Abstract read
In one paragraph

Article in Plant, cell & environment, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Barbara KarpinskaSchool of Biosciences, University of Birmingham, Birmingham, UK.
Alessandro FiocchiDepartment of Pediatrics, Division of Allergy, Pediatric Hospital Bambino Gesù IRCCS, Vatican City, Italy.
Marta BiolattiSoremartec Italia Srl - Technical & Scientific Direction, Alba, Italy.
Ileana ManeraSoremartec Italia Srl - Technical & Scientific Direction, Alba, Italy.
Christine Helen FoyerSchool of Biosciences, University of Birmingham, Birmingham, UK.ORCID https://orcid.org/0000-0001-5989-6989

Funding

This study was financially supported by Soremartec Italia S.r.l. Ferrero Group.
6 · The paper itself

Abstract

Serious allergic reactions are increasing globally. Within this context, fatal anaphylaxis from hazelnut allergies is a critical public health concern. Hazelnuts, which are a common ingredient of many foods, contain many proteins that cause severe allergic reactions. Hazelnuts from all of the major commercial growing locations worldwide contained Spirosoma pollinicola sp. proteins. This endotoxin-producing bacterium is linked to the allergenicity of hazelnut pollen. We were unable to remove the contamination by S. pollinicola proteins, showing that this bacterium is a seed endosymbiont. Comparative proteomics revealed significant variations in the allergenic protein composition of nuts that correlated with patient immune responses. Hazelnuts from provenances 17 and 18 exhibited lower levels of key antigens, particularly Cor a 9 and Cor a 14, highlighting their potential as candidates for genetic modification to mitigate allergenicity. Moreover, Spirosoma protein persistence may influence hazelnut allergenicity and the patient's immune response.

Indexed as

AllergensCorylusSeedsHumansNut HypersensitivityPlant ProteinsProteomicsAllergensPlant Proteinshazelnutsimmune responseprotein allergiesproteomicsseedsskin prick testSpirosoma

Identifiers

PMID41048067
PMCPMC12675980

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.