Evidence map›Paper›PMID 41047818›Full record

ArticleAngewandte Chemie (International ed. in English)2025

Naphthalimide-Based Type-I Nano-Photosensitizers for Enhanced Antitumor Photodynamic Therapy: H

Huiyu Niu, Songnan Wang, Yang Liu, Nana Ma, Shuaiwei Cheng, Beidou Feng, Hyunsun Jeong, Yonggang Yang, Ge Wang, Tony D James and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Sequential HAngewandte Chemie (International ed. in English) · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Huiyu NiuKey Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan International Joint Laboratory of Smart Molecules and Identification and Diagnostic Functions, Collaborative Innovation Centre of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan, 453007, P.R. China.
Songnan WangKey Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan International Joint Laboratory of Smart Molecules and Identification and Diagnostic Functions, Collaborative Innovation Centre of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan, 453007, P.R. China.
Yang LiuKey Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan International Joint Laboratory of Smart Molecules and Identification and Diagnostic Functions, Collaborative Innovation Centre of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan, 453007, P.R. China.
Nana MaKey Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan International Joint Laboratory of Smart Molecules and Identification and Diagnostic Functions, Collaborative Innovation Centre of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan, 453007, P.R. China.
Shuaiwei ChengKey Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan International Joint Laboratory of Smart Molecules and Identification and Diagnostic Functions, Collaborative Innovation Centre of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan, 453007, P.R. China.
Beidou FengKey Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan International Joint Laboratory of Smart Molecules and Identification and Diagnostic Functions, Collaborative Innovation Centre of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan, 453007, P.R. China.
Hyunsun JeongDepartment of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, South Korea.
Yonggang YangKey Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan International Joint Laboratory of Smart Molecules and Identification and Diagnostic Functions, Collaborative Innovation Centre of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan, 453007, P.R. China.
Ge WangCollege of Basic Medicine, Xinxiang Medical University, Xinxiang, Henan, 453007, P.R. China.
Tony D JamesKey Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan International Joint Laboratory of Smart Molecules and Identification and Diagnostic Functions, Collaborative Innovation Centre of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan, 453007, P.R. China.
Juyoung YoonDepartment of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, South Korea.ORCID 0000-0002-1728-3970
Jonathan L SesslerDepartment of Chemistry, The University of Texas at Austin, Austin, 78712-1224, USA.
Hua ZhangKey Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan International Joint Laboratory of Smart Molecules and Identification and Diagnostic Functions, Collaborative Innovation Centre of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan, 453007, P.R. China.

Funding

Biomedical Applications of Expanded Porphyrins: Development of Gold-Texaphyrin ConjugatesR01CA068682 · NCI · UNIVERSITY OF TEXAS AUSTIN · PI Esther Y. Maier, Emily L Que · 1995 to 2026
$7.4M
Henan Province Central Leading Local Science and Technology Development Fund Project Z20231811083Ministry of Science and ICT RS-2024-00407093National Institute of Health-National Cancer InstituteNational Institutes of Health-National Cancer Institute CA 068682National Natural Science Foundation of China 22208087National Natural Science Foundation of China 22378100National Natural Science Foundation of China U21A20314National Research Foundation of Korea RS-2023-00217701NCI NIH HHS R01 CA068682Program for Innovative Research Team in Science and Technology in University of Henan Province 23IRTSTHN002University of Bath and the Open Research Fund of the School of Chemistry and Chemical Engineering, Henan Normal University 2020ZD01Welch Foundation F-0018
6 · The paper itself

Abstract

Photodynamic therapy (PDT) relies on a combination of light and photosensitizers (PSs) to achieve local control over cancerous lesions. However, it is subject to limitations, including tumor hypoxia, low tumor targeting, off-target phototoxicity, and always-on fluorescence. Here, we propose a design strategy for activated nano-PSs (N-PSs) to simultaneously overcome the limitations of PDT, wherein photoinduced electron transfer (PeT) is coupled with an endogenous H

Indexed as

Antineoplastic AgentsHydrogen SulfideNanoparticlesNaphthalimidesPhotochemotherapyPhotosensitizing AgentsAnimalsCell Line, TumorCell ProliferationElectron TransportHumansMiceAntineoplastic AgentsHydrogen SulfideNaphthalimidesPhotosensitizing AgentsH2SNaphthalimidePhotoinduced electron transferSelf‐assemblyType‐I photosensitizers

Identifiers

PMID41047818
PMCPMC12643349

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.