Evidence map›Paper›PMID 41047810›Full record

ArticleAnnals of Saudi medicine

Detection of

Yüksel Akkaya, Begüm Nalça Erdin, İrfan Aydın, Ayşe Serra Özel, Ahmet Münir Yılmaz, Mustafa Çılkız, İbrahim Halil Kılıç, Zülal Aşçı Toraman

Abstract read
In one paragraph

Article in Annals of Saudi medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Clinical and Microbiological Characteristics of EarlyAntibiotics (Basel, Switzerland) · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yüksel AkkayaFrom the Department of Medical Microbiology, Hamidiye Faculty of Medicine, University of Health Sciences, İstanbul, Türkiye.ORCID 0000-0003-1297-944X
Begüm Nalça ErdinFrom the Department of Medical Microbiology Laboratory of Darıca Training and Research Hospital, University of Health Sciences, Istanbul, Türkiye.
İrfan AydınFrom the Pharmacy Services Department, Health Services Vocational School, Fenerbahçe University, Istanbul, Türkiye.
Ayşe Serra ÖzelFrom the Infectious Diseases Clinic of Ümraniye Training and Research Hospital, University of Health Sciences, İstanbul, Türkiye.
Ahmet Münir YılmazFrom the Department of Emergency Medicine, Abdulkadir Yüksel State Hospital Gaziantep, Şahinbey, Türkiye.
Mustafa ÇılkızFrom the Soil and Crop Science College Station, Texas A&M University, Texas, United States.
İbrahim Halil KılıçFrom the Molecular Biology Department, Faculty of Arts and Sciences, Gaziantep University, Gaziantep, Türkiye.
Zülal Aşçı ToramanFrom the Department of Medical Microbiology, Faculty of Medicine, Firat University, Elazig, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

objectivesThe aim of this study was to determine the virulence of

designRetrospective cohort.

settingSingle-center. MATERIAL AND

methodsThis study was conducted between August 2022 and December 2023 at Ümraniye Training and Research Hospital. ITS1-5.8S-ITS2 and ITS1-ITS4 gene regions of the rDNA gene of

main outcome measuresVariations in SAMPLE SIZE: Forty-four isolates from 31 patients.

resultsAccording to gene regions, nine different variations were identified in our hospital, with VAR-1 being the most common. Twenty-five (80.6%) of the patients died and isolation of the causative agent was between days 1-30 in 13 (41.9%) patients. Antibiotic use, ICU admission rate, and central venous catheter use in patients were 29 (93.6%), 28 (90.3%), and 21 (67.7%), respectively. Hypertension, diabetes mellitus (DM) and septic shock were found in 14 (45.2%), 13 (41.9%) and 10 (32.3%) patients, respectively. Antifungal resistance rates of the isolates were determined as 97.7% and 84.1% for amphotericin B and fluconazole, respectively. No resistance to micafungin and caspofungin was detected. The survival rate with echinocandin use was 22% (4 patients).

conclusionIdentification of gene regions is valuable in determining the pathogenicity of LIMITATIONS: Single center setting; gene regions could not be expressed.

Indexed as

Antifungal AgentsCandida aurisCandidiasisAdultAgedDrug Resistance, FungalFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedPolymerase Chain ReactionRetrospective StudiesTertiary Care CentersTurkeyVirulenceAntifungal AgentsCandidemiadrug resistancepolymerase chain reaction

Identifiers

PMID41047810
PMCPMC12498105

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.