Evidence map›Paper›PMID 41047638›Full record

ArticlePhysiological reports2025

Wearable and noninvasive monitoring of fluid shifts: A pilot study assessing a novel bioimpedance sensor during lower body negative pressure.

Lars Øivind Høiseth, Frida Bremnes, Sigve Nyvik Aas, Anne Thorud, Harald Noddeland

Abstract read
In one paragraph

Article in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lars Øivind HøisethDivision of Emergencies and Critical Care, Oslo University Hospital, Oslo, Norway.ORCID 0000-0003-0669-8297
Frida BremnesMode Sensors AS, Trondheim, Norway.ORCID 0009-0005-3018-2604
Sigve Nyvik AasMode Sensors AS, Trondheim, Norway.ORCID 0000-0003-1196-0632
Anne ThorudDivision of Emergencies and Critical Care, Oslo University Hospital, Oslo, Norway.
Harald NoddelandDivision of Emergencies and Critical Care, Oslo University Hospital, Oslo, Norway.

Funding

Research Council of Norway 313922
6 · The paper itself

Abstract

Fluid extravasation is a prominent feature of several disease processes in acute and critical illness. Bioimpedance at frequencies representing extracellular and total resistance offers an opportunity to monitor fluid shifts. The aim of the present study was to explore if a novel wearable bioimpedance device could monitor fluid shifts during lower body negative pressure (LBNP). Eleven subjects underwent 40 min of LBNP at 30 mmHg. Bioimpedance was measured on the leg, upper back, and thoracic midaxillary line. Changes in resistance were compared using mixed linear regression. Further, hemoglobin and albumin concentrations were measured. Ten subjects completed the protocol. Compared to baseline, both extracellular and total resistance changed to the end of the LBNP exposure at all measurement sites. The mean extracellular resistance changed as follows: leg -6.6% (SD 3.1; p < 0.001), upper back 4.1% (SD 3.5; p < 0.001), and midaxillary line 6.3% (SD 2.8; p < 0.001). The wearable bioimpedance sensor detected the expected extracellular fluid shifts occurring with LBNP. Further clinical studies to explore if fluid extravasation in common pathologic conditions can be measured are warranted.

Indexed as

Electric ImpedanceFluid ShiftsLower Body Negative PressureWearable Electronic DevicesAdultFemaleHumansMaleMonitoring, PhysiologicPilot ProjectsYoung Adultdiagnostic equipmentedemafluid shiftshypovolemialower body negative pressure

Identifiers

PMID41047638
PMCPMC12497891

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.