ArticleCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2025
Comparative Analysis of Intravascular Lithotripsy With and Without Atherectomy in Severely Calcified Coronary Lesions Using OCT and OFDI.
Article in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Review
- Comparative Analysis of Intravascular Lithotripsy With and Without Atherectomy in Severely Calcified Coronary Lesions Using OCT and OFDI.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundIntravascular lithotripsy (IVL) fractures calcified plaques and facilitates lesion expansion; however, unlike atherectomy devices, it does not reduce calcium volume. The therapeutic efficacy and safety of combining IVL with atherectomy remain unclear. Therefore, this study aimed to evaluate, through optical coherence tomography (OCT) or optical frequency domain imaging (OFDI), whether IVL combined with atherectomy provides greater effectiveness compared with IVL alone.
aimsThis study aimed to evaluate, using optical coherence tomography (OCT) and optical frequency domain imaging (OFDI), whether intravascular lithotripsy (IVL) combined with atherectomy provides greater procedural efficacy and safety compared with IVL alone in the treatment of severely calcified coronary lesions.
methodsA retrospective analysis was performed on 33 lesions in 31 patients who underwent IVL-based percutaneous coronary intervention (PCI) with OCT or OFDI. The primary endpoints were post-PCI minimal lumen diameter (MLD) and minimal lumen area (MLA). The secondary endpoints included calcium fracture thickness, lesion expansion rate, and vessel expansion index.
resultsThe mean patient age was 72.3 ± 8.5 years, and 80.6% were men. No significant differences were identified in post-PCI MLD or MLA between the IVL alone and IVL + atherectomy groups (MLD: 2.46 ± 0.38 vs. 2.23 ± 0.56 mm; MLA: 4.9 ± 1.55 vs. 4.19 ± 1.90 mm
conclusionsCombination therapy resulted in a longer procedural time and an increased incidence of myocardial injury. IVL alone may be sufficient in lesions where device delivery is feasible, whereas atherectomy should be performed when IVL delivery is challenging.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.