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ArticleJournal of cancer education : the official journal of the American Association for Cancer Education2025

Association Between Spanish-Language Patient Navigation and Adherence to Multi-Target Stool DNA Testing Among Spanish-Speaking Patients at Sanitas Medical Center.

Mallik Greene, Timo Pew, Shrey Gohil, A Burak Ozbay, Juliana Vanessa Rincón López, Paul Limburg, Martha Duarte

Abstract read
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In one paragraph

Article in Journal of cancer education : the official journal of the American Association for Cancer Education, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mallik GreeneExact Sciences Corporation, 5505 Endeavor Ln, Madison, WI, 53719, USA. magreene@exactsciences.com.
Timo PewExact Sciences Corporation, 5505 Endeavor Ln, Madison, WI, 53719, USA.
Shrey GohilExact Sciences Corporation, 5505 Endeavor Ln, Madison, WI, 53719, USA.
A Burak OzbayExact Sciences Corporation, 5505 Endeavor Ln, Madison, WI, 53719, USA.
Juliana Vanessa Rincón LópezUnisanitas, Bogota, Colombia.
Paul LimburgExact Sciences Corporation, 5505 Endeavor Ln, Madison, WI, 53719, USA.
Martha DuarteSanitas USA, Keralty Hospital Miami, Miami, FL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) screening rates remain low among Spanish-speaking populations, in part due to language barriers. This study examined the association between Spanish-language patient navigation on adherence to multi-target stool DNA (mt-sDNA) testing among Spanish-speaking patients at Sanitas Medical Center (SMC). This retrospective analysis utilized data from Exact Sciences Laboratories LLC. It included Spanish-speaking individuals aged 45 to 75 years who received an mt-sDNA test kit between October 1, 2021, and August 1, 2022. Patients were categorized based on Spanish-language outreach (SLO) or English-language outreach (ELO). Adherence was defined as the percentage of kits that were returned with completed tests and successful results within 365 days of the initial shipment date. Chi-square tests and multivariable logistic regression were used to compare adherence between groups and identify factors associated with adherence. The final sample included 3,101 patients in the SLO group and 1,331 in the ELO group. The SLO group showed a 4.4% absolute increase in adherence compared to the ELO group (64.3% vs. 59.9%, p = 0.006). At 30 days, adherence was already higher among SLO patients (45.1% vs. 41.5%), and this difference persisted throughout the 12-month follow-up period. The increase in adherence was consistent across subgroups, including patients aged 50-64 years (64.4% vs. 58.5%, p = 0.002), males (62.2% vs. 55.5%, p = 0.008), and those seen by primary care providers (64.9% vs. 59.8%, p = 0.029). In adjusted logistic regression, SLO was associated with 20% higher odds of adherence compared to ELO (OR = 1.20, 95% CI 1.05-1.37, p = 0.007). Spanish-language patient navigation was associated with a 4.4% higher adherence to mt-sDNA CRC screening among Spanish-speaking patients. These findings suggest that culturally and linguistically tailored communication may support improved screening participation in underserved populations.

Indexed as

Colorectal cancer screeningHealth disparitiesMt-sDNAPatient navigationSpanish-language outreach

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.