Evidence map›Paper›PMID 41047156›Full record

SynthesisEarly intervention in psychiatry2025

Speech and Language Markers as Longitudinal Predictors of Youth Mental Health: A Systematic Review.

Martin Sellier Silva, Jessica Ahrens, Fiona Meister, Lena Palaniyappan

Abstract readSystematic Review
In one paragraph

Synthesis in Early intervention in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Martin Sellier SilvaDouglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Quebec, Canada.ORCID https://orcid.org/0009-0000-4435-6963
Jessica AhrensDouglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Quebec, Canada.
Fiona MeisterDouglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Quebec, Canada.
Lena PalaniyappanDouglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Quebec, Canada.

Funding

Canada First Research Excellence FundCIHREarly Psychosis Intervention CanadaFonds de Recherche du Québec - Santé FRQS #366934Graham Boeckh FoundationMolson FoundationQuebec Bio-Imaging Network (QBIN)Schizophrenia Society of Canada Foundation
6 · The paper itself

Abstract

introductionSevere mental disorders in young people (< 25 years) are often preceded by subtle changes in communication and thinking, detectable in speech. Speech and language markers are promising for early detection; however, no systematic review has evaluated their prospective utility in predicting mental disorders in youth. We comprehensively reviewed longitudinal studies assessing speech/language markers as predictors of major mental disorder onset or symptom progression in youth.

methodsWe searched for longitudinal studies using recorded speech samples from youth or family members to predict diagnostic changes or symptom severity in major depressive disorder (MDD), psychosis, ADHD, substance use disorder, bipolar disorder, OCD and eating disorders. Risk of bias was assessed using the Newcastle-Ottawa Scale. Our protocol was pre-registered (CRD42024579798).

resultsOf 2260 articles, 11 studies met inclusion criteria, covering MDD (n = 3), psychosis (n = 5) and ADHD (n = 3). No eligible studies were found for OCD, substance use, bipolar or eating disorders. Both manual and computational speech analyses were used, with speech samples from parents and youth. Predictive speech/language markers included parental expressed emotion (MDD, ADHD), formal thought disorder (psychosis) and acoustic/linguistic features (psychosis, ADHD). Study quality was moderate to good (mean score: 5.45/8).

conclusionsExternally validated longitudinal studies on the predictive value of speech/language markers of youth-onset mental disorders are scarce, restricted to a few target disorders and do not allow for variations due to the developmental stage of the samples. Nonetheless, existing studies highlight the potential of applying Natural Language Processing methods to speech samples from both youth and parents for early identification.

Indexed as

LanguageMental DisordersSpeechAdolescentHumansLongitudinal Studiescommunicationpredictionpsychopathologyspeechyouth mental health

Identifiers

PMID41047156
PMCPMC12497510

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.